坦桑尼亚北部姆布卢区神经囊尾蚴病的现状与健康负担
The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania.
作者信息
Mwang'onde Beda John, Chacha Mwita John, Nkwengulila Gamba
机构信息
Department of Biosciences, Solomon Mahlangu College of Science and Education, Sokoine University of Agriculture, P.O. Box 3038, Morogoro, Tanzania.
Department of Zoology and Wildlife Conservation, University of Dar es Salaam, P.O. Box 35064, Dar es Salaam, Tanzania.
出版信息
BMC Res Notes. 2018 Dec 13;11(1):890. doi: 10.1186/s13104-018-3999-9.
OBJECTIVE
The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to assess the community's health burden vis-a-vis neurocysticercosis.
RESULTS
The sero-prevalence of HCC was 16.27%. About 76% of 25 selected human cysticercosis sero-positives had neurocysticercosis suggestive lesions on CT scan and 74% had history of epilepsy. Epilepsy caused 2.8 years of life lost and 2.2 healthy years of life lost due to disability per 1000 person-years in Mbulu. The average DALYs imposed due to neurocysticercosis and epilepsy were 3.0 and 3.9 per 1000 person-years, respectively. Neurocysticercosis is a serious public health concern in northern Tanzania.
目的
本研究的目的是评估坦桑尼亚北部姆布卢区普通社区神经囊尾蚴病的流行程度和健康负担。约1051名随机选取的参与者接受了人体囊尾蚴病筛查。采用囊尾蚴病免疫印迹IgG检测和计算机断层扫描来检测囊尾蚴感染情况。伤残调整生命年（DALYs）用于评估社区相对于神经囊尾蚴病的健康负担。
结果
人体囊尾蚴病血清阳性率为16.27%。在25名选定的人体囊尾蚴病血清阳性者中，约76%在CT扫描上有提示神经囊尾蚴病的病变，74%有癫痫病史。在姆布卢，每1000人年中，癫痫导致2.8年的生命损失和2.2年因残疾导致的健康生命损失。每1000人年中，神经囊尾蚴病和癫痫导致的平均伤残调整生命年分别为3.0和3.9。神经囊尾蚴病是坦桑尼亚北部一个严重的公共卫生问题。
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