Diercks Christian S, Kalmutzki Markus J, Diercks Nicolas J, Yaghi Omar M
Department of Chemistry, University of California, Berkeley, California 94720, United States.
Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
ACS Cent Sci. 2018 Nov 28;4(11):1457-1464. doi: 10.1021/acscentsci.8b00677. Epub 2018 Oct 22.
Alfred Werner's work on the geometric aspects of how ligands bind to metal ions at the end of the 19th century has given rise, in the molecular realm, to organometallic, bioinorganic, and cluster chemistries. By stitching together organic and inorganic units into crystalline porous metal-organic frameworks (MOFs), the connectivity, spatial arrangement, and geometry of those molecular complexes can now be fixed in space and become directly addressable. The fact that MOFs are porous provides additional space within which molecules can further be transformed and their chemistry controlled. An aspect not available in molecular chemistry but a direct consequence of Werner's analysis of coordination complexes is the ability to have multivariable functionality in MOFs to bring about a continuum of chemical environments, within the repeating order of the framework, from which a substrate can sample and be transformed in ways not possible in molecular complex chemistry.
19世纪末，阿尔弗雷德·维尔纳关于配体如何与金属离子结合的几何方面的研究，在分子领域催生了有机金属化学、生物无机化学和簇合物化学。通过将有机和无机单元拼接成晶体多孔金属有机框架（MOF），这些分子复合物的连接性、空间排列和几何形状现在可以在空间中固定下来，并变得可直接操控。MOF具有多孔性这一事实提供了额外的空间，分子可以在其中进一步发生转化并控制其化学反应。MOF具有多变量功能，能在框架的重复结构中产生连续的化学环境，使底物能够以分子络合物化学中不可能的方式进行采样和转化，这是分子化学中所没有的，但却是维尔纳对配位络合物分析的直接结果。
