Emerg Infect Dis. 2019 Jan;25(1):186-187. doi: 10.3201/eid2501.180374.
Multilocus sequence typing has been useful for genotyping pathogens in surveillance and epidemiologic studies. However, it cannot reflect the true relationships of isolates for species with very dynamic genomes. Using a robust genome phylogeny, we demonstrated the limitations of this method for typing Acinetobacter baumannii.
多位点序列分型在监测和流行病学研究中对病原体的基因分型很有用。然而,对于基因组非常活跃的物种来说,它无法反映分离株的真实关系。我们使用稳健的基因组系统发育树证明了该方法在鲍曼不动杆菌分型方面的局限性。