Department of Exercise Physiology, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku, Tokyo, 158-8508, Japan.
Center for Fundamental Education, Teikyo University of Science, Tokyo, Japan.
Aging Clin Exp Res. 2019 Oct;31(10):1451-1459. doi: 10.1007/s40520-018-1093-8. Epub 2018 Dec 18.
This study investigated whether interval walking training (IWT) improves cognitive function and arterial function in older adults.
A total of 68 older adults registered in clinical trials (mean age ± standard deviation, 70 ± 4 years) were randomly assigned to two groups: one group performed IWT (n = 34), and the other performed normal walking training (NWT, n = 34). Participants in the IWT group performed five or more sets of low-intensity walking (duration: 3 min per set; peak aerobic capacity for walking: 40%) followed by high-intensity walking (duration: 3 min per set; peak aerobic capacity for walking: > 70%). The NWT group walked at approximately 50% of the peak aerobic capacity for walking. The IWT and NWT were performed for 20 weeks. Trail making test-A and B and carotid-femoral pulse wave velocity (cfPWV) were measured in both groups at baseline and again at the end of the 20-week study period.
Compared to baseline, time for trail making test-A (IWT group: P = 0.00004, NWT group: P = 0.000006) and B (IWT group: P = 0.03, NWT group: P = 0.003) as well as cfPWV (IWT group: P = 0.000002, NWT group: P = 0.03) decreased significantly after the 20-week study period in both groups. However, cfPWV in the IWT group decreased significantly more than that in the NWT group (P = 0.03).
These results suggested that although both IWT and NWT were similarly effective at improving cognitive function, IWT reduced central arterial stiffness more than NWT.
本研究旨在探讨间歇步行训练(IWT)是否能改善老年人的认知功能和动脉功能。
共有 68 名在临床试验中登记的老年人(平均年龄±标准差,70±4 岁)被随机分为两组:一组进行 IWT(n=34),另一组进行常规步行训练(NWT,n=34)。IWT 组进行五组或更多组低强度步行(每组持续 3 分钟;步行的峰值有氧能力为 40%),然后进行高强度步行(每组持续 3 分钟;步行的峰值有氧能力为>70%)。NWT 组以大约 50%的步行峰值有氧能力行走。IWT 和 NWT 均进行 20 周。在基线和 20 周研究结束时,两组均进行连线测试 A 和 B 以及颈股脉搏波速度(cfPWV)测量。
与基线相比,连线测试 A(IWT 组:P=0.00004,NWT 组:P=0.000006)和 B(IWT 组:P=0.03,NWT 组:P=0.003)以及 cfPWV(IWT 组:P=0.000002,NWT 组:P=0.03)的时间在两组中均显著降低。然而,IWT 组的 cfPWV 下降幅度明显大于 NWT 组(P=0.03)。
这些结果表明,尽管 IWT 和 NWT 均能有效改善认知功能,但 IWT 降低中心动脉僵硬的效果优于 NWT。