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间歇步行训练对老年人认知功能和动脉功能的影响与常规步行训练的比较:一项随机对照试验。

Effects of interval walking training compared to normal walking training on cognitive function and arterial function in older adults: a randomized controlled trial.

机构信息

Department of Exercise Physiology, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku, Tokyo, 158-8508, Japan.

Center for Fundamental Education, Teikyo University of Science, Tokyo, Japan.

出版信息

Aging Clin Exp Res. 2019 Oct;31(10):1451-1459. doi: 10.1007/s40520-018-1093-8. Epub 2018 Dec 18.

Abstract

PURPOSE

This study investigated whether interval walking training (IWT) improves cognitive function and arterial function in older adults.

METHODS

A total of 68 older adults registered in clinical trials (mean age ± standard deviation, 70 ± 4 years) were randomly assigned to two groups: one group performed IWT (n = 34), and the other performed normal walking training (NWT, n = 34). Participants in the IWT group performed five or more sets of low-intensity walking (duration: 3 min per set; peak aerobic capacity for walking: 40%) followed by high-intensity walking (duration: 3 min per set; peak aerobic capacity for walking: > 70%). The NWT group walked at approximately 50% of the peak aerobic capacity for walking. The IWT and NWT were performed for 20 weeks. Trail making test-A and B and carotid-femoral pulse wave velocity (cfPWV) were measured in both groups at baseline and again at the end of the 20-week study period.

RESULTS

Compared to baseline, time for trail making test-A (IWT group: P = 0.00004, NWT group: P = 0.000006) and B (IWT group: P = 0.03, NWT group: P = 0.003) as well as cfPWV (IWT group: P = 0.000002, NWT group: P = 0.03) decreased significantly after the 20-week study period in both groups. However, cfPWV in the IWT group decreased significantly more than that in the NWT group (P = 0.03).

CONCLUSION

These results suggested that although both IWT and NWT were similarly effective at improving cognitive function, IWT reduced central arterial stiffness more than NWT.

摘要

目的

本研究旨在探讨间歇步行训练(IWT)是否能改善老年人的认知功能和动脉功能。

方法

共有 68 名在临床试验中登记的老年人(平均年龄±标准差,70±4 岁)被随机分为两组:一组进行 IWT(n=34),另一组进行常规步行训练(NWT,n=34)。IWT 组进行五组或更多组低强度步行(每组持续 3 分钟;步行的峰值有氧能力为 40%),然后进行高强度步行(每组持续 3 分钟;步行的峰值有氧能力为>70%)。NWT 组以大约 50%的步行峰值有氧能力行走。IWT 和 NWT 均进行 20 周。在基线和 20 周研究结束时,两组均进行连线测试 A 和 B 以及颈股脉搏波速度(cfPWV)测量。

结果

与基线相比,连线测试 A(IWT 组:P=0.00004,NWT 组:P=0.000006)和 B(IWT 组:P=0.03,NWT 组:P=0.003)以及 cfPWV(IWT 组:P=0.000002,NWT 组:P=0.03)的时间在两组中均显著降低。然而,IWT 组的 cfPWV 下降幅度明显大于 NWT 组(P=0.03)。

结论

这些结果表明,尽管 IWT 和 NWT 均能有效改善认知功能,但 IWT 降低中心动脉僵硬的效果优于 NWT。

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