有氧运动对中老年人脉搏波速度的影响：一项随机对照试验的系统评价和荟萃分析。
The effect of aerobic exercise on pulse wave velocity in middle-aged and elderly people: A systematic review and meta-analysis of randomized controlled trials.
作者信息
Li Gen, Lv Yuanyuan, Su Qing, You Qiuping, Yu Laikang
机构信息
Key Laboratory of Physical Fitness and Exercise, Ministry of Education, Beijing Sport University, Beijing, China.
Department of Strength and Conditioning Training, Beijing Sport University, Beijing, China.
出版信息
Front Cardiovasc Med. 2022 Aug 18;9:960096. doi: 10.3389/fcvm.2022.960096. eCollection 2022.
UNLABELLED
A growing body of research examines the effect of aerobic exercise on pulse wave velocity (PWV) in middle-aged and elderly people, while findings of available studies were conflicting. The aim of this study was to explore the effect of aerobic exercise on PWV in middle-aged and elderly people. Searches were performed in PubMed, Web of Science, and EBSCO databases. Cochrane risk assessment tool was used to evaluate the methodological quality of the included literature. We included studies that satisfied the following criteria: (1) eligible studies should be randomized controlled trials (RCTs); (2) eligible studies should include both an intervention and a control group; (3) eligible studies should use the middle-aged or elderly people as subjects; and (4) eligible studies should use PWV as the outcome measure. From 972 search records initially identified, 11 studies with a total of 12 exercise groups ( = 245) and 11 control groups ( = 239) were eligible for meta-analysis. There was a significant effect of aerobic exercise on reducing PWV in middle-aged and elderly people [weighted mean difference (WMD), -0.75 (95% CI, -1.21 to -0.28), = 0.002]. Specifically, a higher intensity [vigorous-intensity, -0.74 (-1.34 to -0.14), = 0.02; moderate-intensity, -0.68 (-1.49 to 0.12), = 0.10], a younger age [45 years ≤ age < 60 years, -0.57 (-0.78 to -0.37), < 0.00001; age ≥ 60 years, -0.91 (-2.10 to 0.27), = 0.13], a better health status [healthy, -1.19 (-2.06 to -0.31), = 0.008; diseased, -0.32 (-0.64 to -0.01), = 0.04], and a lower basal body mass index (BMI) [BMI < 25, -1.19 (-2.06 to -0.31), = 0.008; 25 ≤ BMI < 30, -0.52 (-0.92 to -0.12), = 0.01; BMI ≥ 30, -0.09 (-0.93 to 0.76), = 0.84] were associatedwith larger reductions in PWV. Aerobic exercise, especially vigorous-intensity aerobic exercise, contributed to reducing PWV in middle-aged and elderly people. The effect of aerobic exercise on improving PWV was associated with characteristics of the participants. Specifically, a younger age, a better health status, and a lower basal BMI contributed to more significant reductions in PWV.
SYSTEMATIC REVIEW REGISTRATION
[https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022337103], identifier [CRD42022337103].
未标注
越来越多的研究探讨了有氧运动对中老年人脉搏波速度（PWV）的影响，然而现有研究结果相互矛盾。本研究旨在探讨有氧运动对中老年人PWV的影响。在PubMed、科学网和EBSCO数据库中进行了检索。使用Cochrane风险评估工具评估纳入文献的方法学质量。我们纳入了符合以下标准的研究：（1）合格研究应为随机对照试验（RCT）；（2）合格研究应包括干预组和对照组；（3）合格研究应以中老年人为研究对象；（4）合格研究应以PWV作为结局指标。从最初识别的972条检索记录中，有11项研究共12个运动组（n = 245）和11个对照组（n = 239）符合荟萃分析的条件。有氧运动对降低中老年人的PWV有显著效果[加权平均差（WMD），-0.75（95%CI，-1.21至-0.28），P = 0.002]。具体而言，更高强度[剧烈强度，-0.74（-1.34至-0.14），P = 0.02；中等强度，-0.68（-1.49至0.12），P = 0.10]、更年轻的年龄[45岁≤年龄<60岁，-0.57（-0.78至-0.37），P < 0.00001；年龄≥60岁，-0.91（-2.10至0.27），P = 0.13]、更好的健康状况[健康，-1.19（-2.06至-0.31），P = 0.008；患病，-0.32（-0.64至-0.01），P = 0.04]以及更低的基础体重指数（BMI）[BMI < 25，-1.19（-2.06至-0.31），P = 0.008；25≤BMI < 30，-0.52（-0.92至-0.12），P = 0.01；BMI≥30，-0.09（-0.93至0.76），P = 0.84]与PWV的更大降低相关。有氧运动，尤其是剧烈强度的有氧运动，有助于降低中老年人的PWV。有氧运动对改善PWV的效果与参与者的特征有关。具体而言，更年轻的年龄、更好的健康状况和更低的基础BMI有助于更显著地降低PWV。
系统评价注册
[https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022337103]，标识符[CRD42022337103]。
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