TrichoLAB, Warsaw, Poland.
Department of Dermatology, CSK MSWiA, Warsaw, Poland.
Australas J Dermatol. 2019 May;60(2):134-136. doi: 10.1111/ajd.12964. Epub 2018 Dec 18.
The Sinclair Scale of hair midline density is commonly used in clinical dermatology practice as a tool to evaluate the severity of female pattern hair loss (synonym androgenetic alopecia, AGA) and to monitor patient response to treatment. The Sinclair Scale involves a visual evaluation of central hair parting line width, that is performed quickly and with no optical instrumentation. Another approach used to score severity of hair loss is quantitative trichoscopy. While quantitative trichoscopy is more accurate in terms of reproducibility and objectivity, it is more time-consuming.
Patients with different stages of AGA were evaluated using both the Sinclair Scale and quantitative trichoscopy. A correlation analysis was performed between the Sinclair Scale and different parameters derived from statistical analysis of trichoscopy images. A novel parameter, cumulative hair thickness density was introduced.
Very good correlation was observed between Sinclair Scale and the cumulative hair thickness density. The quality of correlation is sufficient to estimate Sinclair Scale from cumulative hair thickness density. A formula to calculate the 'Trichoscopy Derived Sinclair Scale' from trichoscopy statistics was derived.
We propose the term 'Trichoscopy Derived Sinclair Scale' to describe the hair midline density as derived from trichoscopy and to differentiate this assessment of midline hair density from the traditional one based on visual inspection alone.
Sinclair 毛发中线密度分级量表常用于临床皮肤科实践，作为评估女性型脱发（同义词为雄激素性脱发，AGA）严重程度和监测患者对治疗反应的工具。 Sinclair 分级量表涉及对中央发缝宽度的视觉评估，该评估快速进行，无需光学仪器。另一种用于评分脱发严重程度的方法是定量毛发镜检查。虽然定量毛发镜检查在可重复性和客观性方面更准确，但它更耗时。
使用 Sinclair 分级量表和定量毛发镜检查评估不同 AGA 阶段的患者。对 Sinclair 分级量表与从毛发镜图像统计分析得出的不同参数之间进行相关性分析。引入了一个新的参数，即累积毛发厚度密度。
Sinclair 分级量表与累积毛发厚度密度之间观察到非常好的相关性。相关性的质量足以从累积毛发厚度密度估计 Sinclair 分级量表。从毛发镜统计数据中计算“毛发镜检查衍生 Sinclair 分级量表”的公式。
我们提出“毛发镜检查衍生 Sinclair 分级量表”一词来描述源自毛发镜检查的毛发中线密度，并将这种中线毛发密度的评估与仅基于视觉检查的传统评估区分开来。
