Wedzicha J A, Wallis P J, Ingram D A, Empey D W
Department of Thoracic Medicine, London Hospital.
Thorax. 1988 Sep;43(9):729-30. doi: 10.1136/thx.43.9.729.
The effect of a single dose of diazepam on sleep and respiration was studied in nine patients with chronic airflow obstruction with moderate arterial hypoxaemia but no hypercapnia. Diazepam improved sleep duration without exacerbating nocturnal hypoxaemia and there was no change in the number of apnoeic events after a single 5 mg dose at night.
在9例患有慢性气流阻塞且伴有中度动脉低氧血症但无高碳酸血症的患者中，研究了单剂量地西泮对睡眠和呼吸的影响。地西泮改善了睡眠时间，且未加重夜间低氧血症，夜间单次服用5毫克剂量后呼吸暂停事件的数量没有变化。
