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用于青光眼筛查的居家视野测试与汉弗莱视野计的比较

Home-based visual field test for glaucoma screening comparison with Humphrey perimeter.

作者信息

Tsapakis Stylianos, Papaconstantinou Dimitrios, Diagourtas Andreas, Kandarakis Stylianos, Droutsas Konstantinos, Andreanos Konstantinos, Brouzas Dimitrios

机构信息

1st Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece,

出版信息

Clin Ophthalmol. 2018 Dec 12;12:2597-2606. doi: 10.2147/OPTH.S187832. eCollection 2018.

Abstract

PURPOSE

To present a home-based visual field examination method using a PC monitor or virtual reality glasses and evaluate the reliability of the method by comparing the results with those of the Humphrey perimeter, in order to assess the possibility of glaucoma screening through the Internet.

MATERIALS AND METHODS

Software implementing a supra-threshold algorithm for the central 24° (52 points) of visual field at three threshold levels: 1) -4 db, 2) -8 db, and 3) -12 db, from the age-expected sensitivity was used for the purpose of testing. The software uses the web camera as a "virtual photometer" in order to detect room luminosity and allows self-testing using a computer monitor or virtual reality glasses using an Android smartphone with a 6-inch display. The software includes an expert system to analyze the visual field image and validate the reliability of the results. It also allows the physician to combine the results from two or more tests into a single test in order to achieve higher statistical accuracy of the final result. A total of ten patients, 20 eyes tested×52 points per eye=1,040 visual field test points, were compared point to point to those obtained using the Humphrey perimeter for the same patients, as they appeared randomly and consecutively at the glaucoma department within hours.

RESULTS

Good receiver operating characteristic/area under the curve coefficient was found, ranging from 0.762 to 0.837 (<0.001). Sensitivity ranged from 0.637 to 0.942, and specificity ranged from 0.735 to 0.497.

CONCLUSION

The home-based visual field test exhibits a reasonable receiver operating characteristic curve when compared to the Humphrey perimeter, without the need of specialized equipment. The test may be useful for glaucoma screening.

摘要

目的

介绍一种使用电脑显示器或虚拟现实眼镜进行的居家视野检查方法,并通过将结果与汉弗莱视野计的结果进行比较来评估该方法的可靠性,以评估通过互联网进行青光眼筛查的可能性。

材料与方法

使用一种软件,该软件针对视野中央24°(52个点)实施超阈值算法,设置三个阈值水平:1)-4 dB,2)-8 dB,3)-12 dB,以年龄预期敏感度为基础用于测试。该软件将网络摄像头用作“虚拟光度计”以检测室内亮度,并允许使用电脑显示器或通过带有6英寸显示屏的安卓智能手机连接虚拟现实眼镜进行自我测试。该软件包括一个专家系统,用于分析视野图像并验证结果的可靠性。它还允许医生将两次或更多次测试的结果合并为一次测试,以提高最终结果的统计准确性。共有10名患者,20只眼睛接受测试,每只眼睛52个点,共1040个视野测试点,将这些点与同一患者使用汉弗莱视野计在数小时内随机且连续地在青光眼科室获得的测试点逐点进行比较。

结果

发现了良好的受试者工作特征曲线/曲线下面积系数,范围从0.762至0.837(<0.001)。敏感度范围为0.637至0.942,特异度范围为0.735至0.497。

结论

与汉弗莱视野计相比,居家视野测试在无需专门设备的情况下展现出合理的受试者工作特征曲线。该测试可能对青光眼筛查有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a2e/6296209/49df51295256/opth-12-2597Fig2.jpg

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