Shehata Mena, Zaid Fouad, Ottaviano Peter, Shweihat Yousef, Munn Nancy
Department of Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Department of Pulmonary Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Respir Med Case Rep. 2018 Dec 19;26:131-135. doi: 10.1016/j.rmcr.2018.12.006. eCollection 2019.
Malignant pleural mesothelioma (MPM) is an asbestos-related tumor arising in the pleural cavity. Symptoms reflect extension of disease and include shortness of breath and chest pain. Unexplained pleural effusion and pleural pain in patients exposed to asbestos should raise the suspicion of MPM. The most common radiologic presentation is ipsilateral pleural effusion with or without pleural thickening or a mass. Thoracoscopic biopsy remains the most appropriate procedure for definitive diagnosis of mesothelioma. Despite advancement in diagnostic procedures and biomolecular research, this tumor nevertheless has poor prognosis. Mesothelioma remains a diagnostic and therapeutic challenge and is likely to remain one in the years to come. Here we present the first reported case of steroid treatment responsive pleural effusion in a 72 year-old-male that initially was misdiagnosed as rheumatoid related effusion. However, Pleuroscopy with biopsy revealed mesothelioma.
恶性胸膜间皮瘤（MPM）是一种发生于胸腔的与石棉相关的肿瘤。症状反映疾病的进展，包括呼吸急促和胸痛。接触石棉的患者出现不明原因的胸腔积液和胸痛应怀疑MPM。最常见的放射学表现是同侧胸腔积液，伴或不伴有胸膜增厚或肿块。胸腔镜活检仍然是确诊间皮瘤的最合适方法。尽管诊断程序和生物分子研究取得了进展，但这种肿瘤的预后仍然很差。间皮瘤仍然是诊断和治疗上的挑战，并且在未来几年可能依然如此。在此，我们报告首例72岁男性类固醇治疗反应性胸腔积液病例，该病例最初被误诊为类风湿性相关胸腔积液。然而，经胸膜镜检查及活检发现为间皮瘤。
