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亚急性皮肤型红斑狼疮:13例临床病理研究结果

Subacute cutaneous lupus erythematosus: clinicopathologic findings in thirteen cases.

作者信息

Herrero C, Bielsa I, Font J, Lozano F, Ercilla G, Lecha M, Ingelmo M, Mascaró J M

机构信息

Department of Dermatology, Hospital Clinico, Barcelona, Spain.

出版信息

J Am Acad Dermatol. 1988 Dec;19(6):1057-62. doi: 10.1016/s0190-9622(88)70272-8.

DOI:10.1016/s0190-9622(88)70272-8
PMID:3060484
Abstract

The clinicopathologic and serologic findings of thirteen patients with subacute cutaneous lupus erythematosus are reported. The clinical and immunologic features are similar to those described by most other authors. From a histologic point of view, however, two aspects could be emphasized: the presence of a larger number of epidermal colloid bodies and severe epidermal necrosis (more than 60% of cases). All patients with this microscopic picture have a similar clinical and serologic pattern: annular lesions, anti-Ro antibodies and human leukocyte antigen-DR3.

摘要

报告了13例亚急性皮肤型红斑狼疮患者的临床病理和血清学检查结果。其临床和免疫学特征与大多数其他作者所描述的相似。然而,从组织学角度来看,可以强调两个方面:存在大量表皮胶样小体和严重的表皮坏死(超过60%的病例)。所有具有这种显微镜表现的患者都有相似的临床和血清学模式:环形皮损、抗Ro抗体和人类白细胞抗原DR3。

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Subacute cutaneous lupus erythematosus: clinicopathologic findings in thirteen cases.亚急性皮肤型红斑狼疮:13例临床病理研究结果
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[Subacute cutaneous lupus erythematosus based on a study of 15 cases].[基于15例研究的亚急性皮肤型红斑狼疮]
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Immunogenetic findings in cutaneous lupus erythematosus.皮肤红斑狼疮的免疫遗传学研究结果。
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The immunology of cutaneous lupus erythematosus.
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Clinical, histological and immunopathological features of 58 patients with subacute cutaneous lupus erythematosus. A review by the Italian group of immunodermatology.58例亚急性皮肤型红斑狼疮患者的临床、组织学和免疫病理学特征。意大利免疫皮肤病学组的综述
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A monoclonal Ro-antibody and the serum of a Ro-positive patient with subacute cutaneous lupus erythematosus (SCLE) react with basal layers of human epidermis.一种单克隆Ro抗体和一名患有亚急性皮肤型红斑狼疮(SCLE)的Ro阳性患者的血清与人类表皮的基底层发生反应。
Eur J Clin Invest. 1988 Oct;18(5):465-71. doi: 10.1111/j.1365-2362.1988.tb01041.x.
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Histopathologic findings in cutaneous lupus erythematosus.皮肤红斑狼疮的组织病理学表现。
Arch Dermatol. 1994 Jan;130(1):54-8.

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