Department of Public Health, Institute of Health Sciences, Faculty of Medicine, Vilnius University, Vilnius, M.K Ciurlionio str. 21, 03101, Vilnius, Lithuania.
Clinic of Children's Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Antakalnio str. 57, 10207, Vilnius, Lithuania.
Eur J Pediatr. 2019 Mar;178(3):369-376. doi: 10.1007/s00431-018-3306-8. Epub 2019 Jan 4.
The quality of life for the family is an important outcome of childhood asthma. The aim of the study was to describe the quality of life in families who have a child with asthma. The Pediatric Quality of Life Inventory Family Impact Module was completed by the parents of 527 children with asthma. The median overall score was 75.0 (interquartile range 63.9, 87.5). The following factors were independently associated with lower quality of life: additional difficulties such as anxiety and financial hardship (3.81 [2.45, 5.93]), waking with asthma symptoms one or more nights a week (odds ratio 2.53 [1.34, 4.75]), regular use of symptoms reliever medication (2.47 [1.57, 3.87]), and female gender (1.97 [1.27, 3.05]). Lower socioeconomic status of the family and exposure to molds at home doubled the odds for lower quality of life. Physician's diagnosed asthma severity and control were associated with quality of life in univariate, but not multivariate analysis.Conclusion: Multiple factors, several of which are not related to asthma, contribute to the family burden of having a child with asthma. Clinicians should be mindful of the impact of asthma on the child and the family, and consider exploring factors not directly related to childhood asthma. What is Known: • Childhood asthma as a chronic disease impacts the quality of life of the patient, but there is also an impact on the immediate family. • There are relatively few studies exploring the quality of life of parents of a child with asthma; the results are heterogeneous and none has been carried out in an Eastern European country. What is New: • This is the first study to describe caregiver's quality of life in an Eastern European population in the context of childhood asthma. • The quality of life of the family of asthmatic child depends not only on factors related to asthma, but also non-asthma related factors such as poverty which play even more important role.
家庭生活质量是儿童哮喘的一个重要结果。本研究旨在描述哮喘患儿家庭的生活质量。527 名哮喘患儿的父母完成了儿童生活质量调查问卷家庭影响模块。总体中位数评分为 75.0(四分位距 63.9,87.5)。生活质量较低的独立相关因素包括:存在其他困难,如焦虑和经济困难(3.81[2.45,5.93])、每周有一到两个晚上因哮喘症状而醒来(比值比 2.53[1.34,4.75])、定期使用症状缓解药物(2.47[1.57,3.87])和女性(1.97[1.27,3.05])。家庭社会经济地位较低和家中存在霉菌会使生活质量较低的几率翻倍。医生诊断的哮喘严重程度和控制情况与生活质量相关,但在多变量分析中无相关性。结论:有多个因素会导致患儿家庭负担加重,其中有几个因素与哮喘无关。临床医生应该注意哮喘对儿童和家庭的影响,并考虑探索与儿童哮喘无关的因素。已知:•儿童哮喘作为一种慢性疾病,会影响患者的生活质量,但也会对其直系亲属产生影响。• 有相对较少的研究探讨哮喘患儿父母的生活质量;结果存在异质性,且在东欧国家尚无相关研究。新发现:•这是第一项在东欧人群中描述哮喘患儿照顾者生活质量的研究。•哮喘患儿家庭的生活质量不仅取决于与哮喘相关的因素,还取决于贫困等非哮喘相关因素,这些因素的作用更为重要。