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母乳对支气管肺发育不良婴儿呼吸结局的影响。

Impact of breast milk on respiratory outcomes in infants with bronchopulmonary dysplasia.

机构信息

Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Pediatr Pulmonol. 2019 Mar;54(3):313-318. doi: 10.1002/ppul.24228. Epub 2019 Jan 4.

DOI:10.1002/ppul.24228
PMID:30609293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6518393/
Abstract

BACKGROUND

The objective of our study was to examine whether outpatient respiratory morbidities in infants with bronchopulmonary dysplasia (BPD) are influenced by the human milk consumption.

METHODS

Caregivers of subjects recruited from a BPD clinic completed questionnaires regarding breast milk intake and respiratory outcomes.

RESULTS

One-hundred eighty-eight caregivers completed the questionnaire. Of these, 173 (92.0%) reported that the child received some breast milk. Infants who received breast milk for fewer months were more likely to be non-white, and have a lower household income, public insurance, and secondhand smoke exposure. A longer receipt of breast milk was associated with reduced likelihoods of emergency department visits, systemic steroid courses, and cough or chest congestion, and a trend towards a lower risk of re-hospitalizations.

CONCLUSIONS

Longer duration of breast milk intake was associated with markers of higher socio-economic status, and reduced likelihood of acute and chronic respiratory morbidities among preterm infants with bronchopulmonary dysplasia.

摘要

背景

本研究旨在探讨支气管肺发育不良(BPD)婴儿门诊呼吸系统疾病是否受人乳摄入量的影响。

方法

从 BPD 门诊招募的受试对象的照顾者完成了有关母乳摄入和呼吸结果的问卷。

结果

188 位照顾者完成了问卷。其中,173 位(92.0%)报告说孩子接受了一些母乳。接受母乳时间较短的婴儿更有可能是非白人,家庭收入较低,有公共保险和二手烟暴露。较长时间的母乳喂养与急诊就诊、全身类固醇疗程、咳嗽或胸部充血的可能性降低以及再住院的风险降低有关。

结论

BPD 早产儿接受母乳时间较长与更高的社会经济地位指标有关,且与急性和慢性呼吸系统疾病的可能性降低有关。

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Human Milk Oligosaccharide Concentrations Are Associated with Multiple Fixed and Modifiable Maternal Characteristics, Environmental Factors, and Feeding Practices.人乳低聚糖浓度与多种固定和可改变的母体特征、环境因素以及喂养方式有关。
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Breastfeeding and the Developmental Origins of Asthma: Current Evidence, Possible Mechanisms, and Future Research Priorities.
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Nutrients. 2023 Jul 28;15(15):3353. doi: 10.3390/nu15153353.
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Human Milk Feeding Is Associated with Decreased Incidence of Moderate-Severe Bronchopulmonary Dysplasia in Extremely Preterm Infants.母乳喂养与极早产儿中重度支气管肺发育不良发病率降低有关。
Children (Basel). 2023 Jul 23;10(7):1267. doi: 10.3390/children10071267.
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A review and guide to nutritional care of the infant with established bronchopulmonary dysplasia.对已确诊支气管肺发育不良婴儿的营养护理的综述和指南。
J Perinatol. 2023 Mar;43(3):402-410. doi: 10.1038/s41372-022-01578-0. Epub 2022 Dec 9.
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Nutrients. 2022 Aug 12;14(16):3311. doi: 10.3390/nu14163311.
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