Alabi Rolake O, Ansin Amy, Clover Jameson, Wilkins John, Rao Naveen K, Terry Mark A, Tran Khoa D, Sales Christopher S
Department of Ophthalmology, Weill Cornell Medical College, New York, NY.
Vision Research Laboratory, Lions VisionGift, Portland, OR.
Cornea. 2019 Apr;38(4):509-514. doi: 10.1097/ICO.0000000000001848.
To determine the feasibility of using telemedicine consultations in the evaluation of recovered donor corneas for transplant suitability.
This study aims to establish and test the minimum imaging requirements for telemedical consultations of corneal tissue by remote eye bank medical directors. Digital images from the slit lamp, optical coherence tomography, and/or specular microscope were assembled into telemedical consults and emailed to 4 eye bank medical directors (M.A.T., J.W., C.S.S., N.K.R.). Feedback on the minimum image requirements for each corneal finding was collected. After establishing a standardized imaging and presentation protocol, test cases were presented to the medical directors to examine the validity of these remote consults. To establish a benchmark for the study's parameters, one medical director (J.W.) examined each case in person after his initial remote review. Examiners were masked to each other's responses.
Minimum image requirements for determination of corneal findings were defined and were specific to each anatomic layer of the cornea (epithelial, stromal, or endothelial). Using a defined set of digital images for a set of common corneal findings, the rate of agreement between remote evaluators, eye bank staff, and the in-person evaluator was 100% (11 of 11 examples). For ambiguous test cases, remote evaluators agreed on 80% of the cases (4 of 5).
Results from this pilot study suggest that telemedical review of corneal tissue using high-quality digital images may be adequate for accurate identification of specific corneal findings commonly encountered by eye banks.
确定使用远程医疗会诊评估恢复的供体角膜移植适宜性的可行性。
本研究旨在确定并测试远程眼库医学主任对角膜组织进行远程医疗会诊的最低成像要求。将来自裂隙灯、光学相干断层扫描和/或镜面显微镜的数字图像整理成远程医疗会诊资料,并通过电子邮件发送给4位眼库医学主任(M.A.T.、J.W.、C.S.S.、N.K.R.)。收集关于每种角膜病变最低图像要求的反馈。在建立标准化的成像和展示方案后,向医学主任展示测试病例,以检验这些远程会诊的有效性。为确定研究参数的基准,一位医学主任(J.W.)在最初的远程评估后亲自检查每个病例。检查人员对彼此的回答不知情。
确定了角膜病变诊断的最低图像要求,且这些要求针对角膜的每个解剖层(上皮层、基质层或内皮细胞层)都有其特异性。对于一组常见的角膜病变,使用一组定义好的数字图像,远程评估人员、眼库工作人员和亲自评估人员之间的一致率为100%(11个例子中的11个)。对于不明确的测试病例,远程评估人员在80%的病例上达成了一致(5个中的4个)。
这项初步研究的结果表明,使用高质量数字图像对角膜组织进行远程医疗评估可能足以准确识别眼库常见的特定角膜病变。