Católica Lisbon School of Business and Economics, Universidade Católica Portuguesa, Lisbon, Portugal.
Centro de Estudos de Medicina Baseada na Evidência (CEMBE), Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
ESC Heart Fail. 2019 Apr;6(2):254-261. doi: 10.1002/ehf2.12399. Epub 2019 Jan 8.
Heart failure (HF) is a clinical syndrome with significant social and economic burden. We aimed to estimate the burden of HF in mainland Portugal over a 22-year time horizon, between 2014 and 2036.
Heart failure burden was measured in disability-adjusted life years (DALYs), resulting from the sum of years of life lost (YLL) due to premature death and years lost due to disability (YLD). YLL were estimated based on the Portuguese mortality rates reported by the European Detailed Mortality Database. For YLD, disease duration and the overall incidence were estimated using an epidemiological model developed by the World Health Organization (DISMOD II). Disability weights were retrieved from published literature. The impact of ageing was estimated with a shift-share analysis using official demographic projections. In 2014, 4688 deaths were attributed to HF, corresponding to 4.7% of the total deaths in mainland Portugal. DALYs totalled 21 162, 53.9% due to premature death (YLL: 11 398) and 46.1% due to disability (YLD: 9765). Considering only population ageing over a 22-year horizon, the deaths and burden of HF are expected to increase by 73.0% and 27.9%, respectively, reaching 8112 deaths and 27 059 DALYs lost due to HF in 2036. DALY's growth is mainly driven by the increase of YLL, whose contribution to overall burden will increase to 62.0%.
Heart failure is an emerging and growing health problem where significant health gains may be obtained. The projected significant increase of HF burden highlights the need to set HF as a priority for healthcare system.
心力衰竭(HF)是一种具有重大社会和经济负担的临床综合征。我们旨在估计 2014 年至 2036 年 22 年内葡萄牙本土 HF 的负担。
通过残疾调整生命年(DALY)衡量心力衰竭负担,该指标是由过早死亡导致的生命年损失(YLL)和因残疾导致的生命年损失(YLD)的总和。YLL 是根据欧洲详细死亡率数据库报告的葡萄牙死亡率估计的。对于 YLD,使用世界卫生组织(DISMOD II)开发的流行病学模型估计疾病持续时间和总体发病率。残疾权重从已发表的文献中检索。使用官方人口预测进行的份额转移分析来估计老龄化的影响。2014 年,有 4688 人死于 HF,占葡萄牙本土总死亡人数的 4.7%。DALY 总计 21162 人,53.9%是由于过早死亡(YLL:11398),46.1%是由于残疾(YLD:9765)。仅考虑 22 年内的人口老龄化,HF 的死亡人数和负担预计将分别增加 73.0%和 27.9%,到 2036 年,HF 死亡人数将达到 8112 人,DALY 损失将达到 27059 人。DALY 的增长主要是由 YLL 的增加驱动的,其对总负担的贡献将增加到 62.0%。
HF 是一个新兴且不断增长的健康问题,在该问题上可能会取得重大健康收益。HF 负担预计会显著增加,这突显了将 HF 作为医疗保健系统优先事项的必要性。