Bretaudeau Clemence, Vaysse Charlotte, Guerby Paul, Lairez Olivier, Soule-Tholy Marc, Vidal Fabien, Chantalat Elodie
Department of Gynaecology Surgery, CHU Paule de Viguier, Toulouse, France.
Department of Gynaecology Surgery, CHU Rangueil, Toulouse, France.
Cardiol Res. 2018 Dec;9(6):381-384. doi: 10.14740/cr756w. Epub 2018 Dec 7.
A ruptured breast implant is usually asymptomatic and accidentally discovered during an imaging test. However, implant ruptures can cause isolated silicone granulomas and cases of severe systemic disease. We report the first case of a 39-year-old female patient with augmentation breast implants and myopericarditis secondary to implant rupture. Many etiologies of myopericarditis were explored, but none were selected with the exception of the rupture of the implant in the left breast. Magnetic resonance imaging showed a prosthetic rupture with capsular intrusion and formation of a silicone granuloma with inflammation of the pericardium on contact. Clinical and radiological improvement was observed in the short term after surgical removal of the implant. A review of the literature was conducted supporting the hypothesis of an autoimmune and inflammatory syndrome induced by an adjuvant.
乳房植入物破裂通常无症状，多在影像学检查时偶然发现。然而，植入物破裂可导致孤立性硅肉芽肿及严重的全身性疾病。我们报告首例39岁女性患者，其隆乳植入物破裂继发心肌心包炎。对多种心肌心包炎病因进行了排查，但除左乳植入物破裂外未发现其他病因。磁共振成像显示假体破裂伴包膜侵入，形成硅肉芽肿并累及心包致炎症。手术取出植入物后短期内观察到临床及影像学改善。文献回顾支持佐剂诱导自身免疫和炎症综合征的假说。
