Dias Anabela G, Pinto Diana F S, Borges Maria F, Pereira Maria H, Santos João A M, Cunha Luís T, Lencart Joana
Medical Physics Department, Portuguese Institute of Oncology (IPO-Porto), Porto, Portugal.
Medical Physics, Radiobiology and Radiation Protection Group, Research Centre, Portuguese Institute of Oncology, Porto (CI-IPO), Portugal.
J Appl Clin Med Phys. 2019 Feb;20(2):63-70. doi: 10.1002/acm2.12525. Epub 2019 Jan 9.
In-phantom and in-vivo three dimensional conformal radiation therapy (3DCRT) and volumetric modulated arc therapy (VMAT) skin doses, measured with and without bolus in a female anthropomorphic phantom RANDO and in patients, were compared against treatment planning system calculated values. A thorough characterization of the metal oxide semiconductor field effect transistor measurement system was performed prior to the measurements in phantoms and patients. Patients with clinical indication for postoperative external radiotherapy were selected. Skin dose showed higher values with 3DCRT technique compared with VMAT. The increase in skin dose due to the use of bolus was quantified. It was observed that, in the case of VMAT, the bolus effect on the skin dose was considerable when compared with 3DCRT. From the point of view of treatment time, bolus cost, and positioning reproducibility, the use of bolus in these situations can be optimized.
在女性人体模型RANDO以及患者体内，分别测量了有和没有使用 bolus 时的三维适形放射治疗（3DCRT）和容积调强弧形治疗（VMAT）的皮肤剂量，并将其与治疗计划系统计算值进行比较。在对人体模型和患者进行测量之前，对金属氧化物半导体场效应晶体管测量系统进行了全面表征。选择有术后体外放疗临床指征的患者。与VMAT相比，3DCRT技术的皮肤剂量更高。量化了使用 bolus 导致的皮肤剂量增加。观察到，在VMAT的情况下，与3DCRT相比，bolus 对皮肤剂量的影响相当大。从治疗时间、bolus 成本和定位重复性的角度来看，在这些情况下使用 bolus 可以得到优化。
