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单孔充气式纵隔镜联合腹腔镜辅助小切口手术治疗食管癌是一种有效且安全的方法。

Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery for Radical Esophagectomy Is an Effective and Safe Treatment for Esophageal Cancer.

机构信息

Department of Cardiothoracic Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, 52 East Meihua Road, Xiangzhou District, Zhuhai, 519000, Guangdong, China.

出版信息

J Gastrointest Surg. 2019 Aug;23(8):1533-1540. doi: 10.1007/s11605-018-04069-w. Epub 2019 Jan 11.

Abstract

BACKGROUND

We previously developed a novel non-trans thoracic esophagectomy, the single-port inflatable mediastinoscopy combined with laparoscopy for the radical esophagectomy of esophageal cancer. The purpose of this study was to report its therapeutic efficacy and safety.

METHODS

From May 2016 to August 2017, we have completed 80 cases of radical resection of esophageal carcinoma using this novel surgical technique. The intraoperative findings and postoperative complications were reported.

RESULTS

The operation was successfully performed in all patients except for one patient switched from laparoscopic-assisted operation to open surgery. The mean operation duration was 191.4 ± 27 min, and the mean intraoperative blood loss was 147.3 ± 28.9 mL. The mean number of removed lymph node was 21.9 ± 4.1. Five patients (6.4%) who had preoperative type I respiratory failure needed to stay in the intensive care unit for 24 h postoperatively. Postoperative complications included anastomotic leakage (8.9%), anastomotic stricture (21.25%), pleural effusion (9%), and hoarseness postoperative hoarseness (18.8%). The incidence of hoarseness at 3 months postoperation was reduced to 3.8%. All the complications were Clavien-Dindo grades I-III. There were no perioperative death and postoperative cardiopulmonary complications.

CONCLUSION

These results showed that the single-port inflatable mediastinoscopy combined with laparoscopy is feasible for radical esophagectomy and possesses good therapeutic efficacy and safety.

摘要

背景

我们先前开发了一种新型非经胸食管切除术,即单孔充气纵隔镜联合腹腔镜用于食管癌根治术。本研究旨在报告其治疗效果和安全性。

方法

从 2016 年 5 月至 2017 年 8 月,我们使用这种新的手术技术完成了 80 例食管癌根治性切除术。报道了术中发现和术后并发症。

结果

除 1 例患者从腹腔镜辅助手术转为开放手术外,所有患者均成功完成手术。手术平均时间为 191.4±27 分钟,术中平均出血量为 147.3±28.9 毫升。平均切除淋巴结数为 21.9±4.1 个。术前 I 型呼吸衰竭的 5 例患者(6.4%)需要术后在重症监护病房停留 24 小时。术后并发症包括吻合口漏(8.9%)、吻合口狭窄(21.25%)、胸腔积液(9%)和术后声音嘶哑(18.8%)。术后 3 个月声音嘶哑的发生率降低至 3.8%。所有并发症均为 Clavien-Dindo Ⅰ-Ⅲ级。无围手术期死亡和术后心肺并发症。

结论

这些结果表明,单孔充气纵隔镜联合腹腔镜用于食管癌根治术是可行的,具有良好的治疗效果和安全性。

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