Chen Bingliang, Zhou Bingyan, Song Guoda, Li Hao, Li Rui, Liu Zhuo, Wei Chao, Wang Tao, Wang Shaogang, Ma Delin, Liu Jihong, Yuan Xiaoyi, Liu Xiaming
Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Second Clinical College, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Transl Androl Urol. 2022 Jul;11(7):959-973. doi: 10.21037/tau-22-190.
Several studies report that sexuality is often affected by inflammatory bowel diseases (IBD). The aim of this meta-analysis was to investigate the association between IBD and sexual function.
A literature search was conducted in PubMed, Web of Science, and EMBASE databases (up to September 1, 2020). Scores of sexual functions with a standard deviation and odds ratio (OR) or relative risk (RR) with a 95% CI were used to analysis the association between IBD and sexual function.
Eleven studies with 7,018 male IBD cases and 1,803 female IBD cases were included in the meta-analysis. In male individuals, the pooled results revealed that IBD was significantly associated with impaired erectile function and poor sexual satisfaction (RR for erectile function =1.50, 95% CI: 1.22 to 1.84, P<0.0001; standard mean difference for sexual satisfaction =-0.24, 95% CI: -0.33 to -0.15, P<0.0001). And among female individuals, IBD had impact on most sub-domains of sexual function, except pains.
IBD is associated with worse sexual function. It has significant impact on erectile function and satisfaction for male individuals and has impact on most sub-domains of sexual function for female individuals.
多项研究报告称，炎症性肠病（IBD）常影响性功能。本荟萃分析的目的是研究IBD与性功能之间的关联。
在PubMed、科学网和EMBASE数据库中进行文献检索（截至2020年9月1日）。使用具有标准差的性功能评分以及具有95%置信区间的优势比（OR）或相对风险（RR）来分析IBD与性功能之间的关联。
荟萃分析纳入了11项研究，其中男性IBD病例7018例，女性IBD病例1803例。在男性个体中，汇总结果显示IBD与勃起功能障碍和性满意度低显著相关（勃起功能的RR = 1.50，95%置信区间：1.22至1.84，P < 0.0001；性满意度的标准平均差 = -0.24，95%置信区间：-0.33至-0.15，P < 0.0001）。在女性个体中，IBD对性功能的大多数子领域有影响，但疼痛除外。
IBD与较差的性功能相关。它对男性个体的勃起功能和满意度有显著影响，对女性个体性功能的大多数子领域有影响。
