School of Public Health, College of Public Health, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 11031, Taiwan.
Department of Public Health, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 11031, Taiwan.
BMC Public Health. 2019 Jan 15;19(1):65. doi: 10.1186/s12889-019-6398-9.
Carotid intima media thickness (cIMT) and the carotid plaque score (cPS) are valid markers for detecting subclinical atherosclerosis. Evaluation of ASI and ABI for detection of atherosclerosis is assessed in this study. Finding a model to see which individual has a risk of having atherosclerosis, so those people can be further assessed by invasive but more accurate atherosclerosis detection methods like angiography is another objective of this study.
Data of 212 healthy community-dwelling subjects, consisting of carotid duplex records, ASI and ABI measurements, certain laboratory tests, and related cardiovascular disease (CVD) risks were analyzed for correlations.
The ABI was independently associated with high cPS. Age, hypertension and Waist circumference are determinants of subclinical atherosclerosis as in high cIMT and high cPS.
The use of the ASI cannot replace carotid ultrasound in detecting subclinical atherosclerosis because it is not independently associated with high cIMT and cPS while ABI can be used in detection of high cPS in healthy community-dwelling individuals. Public health policies to encourage weight reduction and treating hypertension can help prevention of subclinical atherosclerosis in healthy community-dwelling individuals. Models consist of age, body compositions like waist circumference and hypertension history can be used in further assessment of atherosclerosis.
颈动脉内膜中层厚度（cIMT）和颈动脉斑块评分（cPS）是检测亚临床动脉粥样硬化的有效标志物。本研究评估了 ASI 和 ABI 检测动脉粥样硬化的能力。寻找一种模型来确定哪些个体有患动脉粥样硬化的风险，以便对这些人进行进一步评估，使用侵入性但更准确的动脉粥样硬化检测方法，如血管造影术，这也是本研究的另一个目标。
分析了 212 名健康社区居民的颈动脉双功能超声记录、ASI 和 ABI 测量值、某些实验室检查和相关心血管疾病（CVD）风险的数据，以确定相关性。
ABI 与高 cPS 独立相关。年龄、高血压和腰围是亚临床动脉粥样硬化的决定因素，与高 cIMT 和高 cPS 有关。
ASI 的使用不能替代颈动脉超声检测亚临床动脉粥样硬化，因为它与高 cIMT 和 cPS 不独立相关，而 ABI 可用于检测健康社区居民的高 cPS。公共卫生政策鼓励减肥和治疗高血压可以帮助预防健康社区居民的亚临床动脉粥样硬化。模型可以包括年龄、腰围等身体成分和高血压病史，用于进一步评估动脉粥样硬化。
