Mozafari Nikoo, Bidari-Zerehpoosh Farahnaz, Movahedi Mahdiyeh, Dadkhahfar Sahar
Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Department of Dermatology, Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.
Clin Case Rep. 2022 Aug 8;10(8):e6191. doi: 10.1002/ccr3.6191. eCollection 2022 Aug.
The lichen planus (LP) is an inflammatory and immune-mediated disorder that can affect the hair, mucous membranes, nails, and skin. Lichen planus rarely affects the lips. In cases of lip involvement, it presents as radiated streaks, lace-like papules, and erosions. There is no report of lip LP presenting as hypertrophic plaque. Here, we report interesting and rare clinical presentations of LP in a 45-year-old male patient that presented with a verrucous hyperkeratotic plaque on the lower lip mimicking squamous cell carcinoma. However, oral examination revealed, reticulated white patches on the bilateral buccal mucosa, and a biopsy of the lip lesion revealed lichenoid dermatitis which led to the diagnosis of hypertrophic lichen planus. Familiarity with the different clinical presentations of LP and its variants is essential for prompt diagnosis and effective treatment.
扁平苔藓（LP）是一种炎症性和免疫介导性疾病，可累及毛发、黏膜、指甲和皮肤。扁平苔藓很少累及唇部。唇部受累时，表现为放射状条纹、花边样丘疹和糜烂。尚无唇部扁平苔藓表现为肥厚性斑块的报道。在此，我们报告了一名45岁男性患者有趣且罕见的扁平苔藓临床表现，其下唇出现疣状角化过度斑块，类似鳞状细胞癌。然而，口腔检查发现双侧颊黏膜有网状白色斑块，唇部病变活检显示苔藓样皮炎，从而诊断为肥厚性扁平苔藓。熟悉扁平苔藓及其变体的不同临床表现对于及时诊断和有效治疗至关重要。
