Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001.
Org Biomol Chem. 2019 Feb 6;17(6):1370-1374. doi: 10.1039/c8ob03211d.
A practical and scalable electrochemical oxidation of S-H and N-H was developed. This oxidant- and catalyst-free electrochemical process enables S-N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.
发展了一种实用且可扩展的电化学 S-H 和 N-H 氧化方法。该无氧化剂和催化剂的电化学过程可在未分隔的电池中使用廉价的镍电极实现 S-N 键形成。该方法具有广泛的底物范围和良好的官能团相容性。50 g 规模的氧化偶联预示着其在工业应用中的良好前景。
