European Academy of Cancer Sciences, Danish Cancer Society Research Centre, Copenhagen, Denmark.
Minister for Science, Technology and Higher Education, Portugal.
Mol Oncol. 2019 Mar;13(3):502-510. doi: 10.1002/1878-0261.12452. Epub 2019 Feb 1.
Today, cancer is a significant challenge for society, healthcare systems and the growing number of affected patients and their families. This article argues that new paradigms and conditions for responsible science and innovation policy across the European Union (EU) require (i) the collective action of Research & Development institutions, (ii) a system approach to health systems, higher education and patient organizations, and (iii) new initiatives to encourage international cooperation across an enlarged Europe; no single country can successfully fight the disease(s) on its own. Recently, a cancer mission was proposed (Celis and Pavalski, ), the origins of which are rooted in the continuous efforts of the research community, cancer patient organizations, member states and the European Commission during nearly two decades to address the fragmentation and lack of coordination of European cancer research; these efforts led to the creation of Cancer Core Europe and Cancer Prevention Europe, consortia aimed at linking therapeutic and prevention geometries. Ultimately, the platform/infrastructure will be composed of networks of Comprehensive Cancer Centres and cancer research centres across Europe to reach the critical mass of expertise, patients and collaborative portfolio of projects that are necessary to promote science-driven and social innovations in the era of personalized (precision) cancer medicine. Employing a mission-oriented approach to achieve the goal of ensuring a long life expectancy for three out of four cancer patients by 2030 is likely to have a particularly positive impact on the way European citizens' value science and knowledge. It will change the lives of many families across Europe and beyond and should be oriented to ensure that Europe is at the forefront when it comes to quality of life. It is our collective responsibility to ensure that not a single person or region in Europe is left behind.
如今，癌症是社会、医疗保健系统以及越来越多受影响的患者及其家庭面临的重大挑战。本文认为，欧盟需要新的范式和负责任的科学与创新政策条件，包括：（i）研发机构的集体行动；（ii）对卫生系统、高等教育和患者组织采取系统方法；（iii）鼓励扩大后的欧洲开展国际合作的新举措；任何一个国家都无法独自成功应对癌症等疾病。最近提出了癌症使命（Celis 和 Pavalski，），其起源可以追溯到研究界、癌症患者组织、成员国和欧盟委员会近二十年来的持续努力，以解决欧洲癌症研究的碎片化和缺乏协调问题；这些努力促成了癌症核心欧洲和欧洲癌症预防联盟的成立，旨在将治疗和预防的几何结构联系起来。最终，该平台/基础设施将由欧洲各地的综合癌症中心和癌症研究中心网络组成，以达到促进个性化（精准）癌症医学时代的科学驱动和社会创新所需的专业知识、患者和合作项目组合的关键质量。采用以任务为导向的方法实现到 2030 年确保四分之三的癌症患者预期寿命延长的目标，很可能会对欧洲公民对科学和知识的价值产生特别积极的影响。它将改变欧洲乃至其他地区许多家庭的生活，应注重确保欧洲在生活质量方面处于领先地位。我们有责任确保欧洲没有一个人或地区掉队。
