Nguyen Quan D, Randall James W, Harmon Taylor S, Robinson Angelica S, Cotes Claudia, Lee Anne E, Mahon Brian H, Sadruddin Sarfaraz
Radiology, University of Texas Medical Branch, Galveston, USA.
Radiation Oncology, University of Texas Medical Branch, Galveston, USA.
Cureus. 2018 Nov 14;10(11):e3594. doi: 10.7759/cureus.3594.
Screening mammography has helped to identify countless incidences of breast cancer since its adoption in the 1960s. Over time, the screening guidelines and techniques have been refined to better detect malignancies and to avoid false positive results. However, weaknesses remain in mammography and represent an opportunity for improvement. The interference of natural breast tissue and glands can obscure the presence of occult breast malignancies. Additionally, the inability to differentiate breast tissue on the basis of depth, and the compounding of breast densities that occurs as a consequence of two-dimensional imaging, are setbacks when it comes to relying on mammography. User error and bias can also misguide the proper detection of underlying cancers during the radiological interpretation process. The following case represents a combination of these factors and others that culminated in a missed diagnosis of invasive ductal carcinoma in a young woman suffering from mastitis of the contralateral breast.
自20世纪60年代采用以来，乳腺筛查钼靶检查已帮助发现了无数例乳腺癌。随着时间的推移，筛查指南和技术不断完善，以更好地检测恶性肿瘤并避免假阳性结果。然而，钼靶检查仍存在不足，这是有待改进的地方。天然乳腺组织和腺体的干扰可能会掩盖隐匿性乳腺恶性肿瘤的存在。此外，无法根据深度区分乳腺组织，以及二维成像导致的乳腺密度叠加，都是依赖钼靶检查时的不利因素。在放射学解读过程中，人为误差和偏差也可能误导对潜在癌症的正确检测。以下病例就是这些因素及其他因素综合作用的结果，最终导致一名患有对侧乳腺炎的年轻女性的浸润性导管癌被漏诊。
