Sholapurkar S L, Gupta A N, Mahajan R C
Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Trans R Soc Trop Med Hyg. 1988;82(3):376-9. doi: 10.1016/0035-9203(88)90124-1.
A prospective hospital-based study was conducted from June 1984 to November 1985 in northern India to study the morbidity pattern of malaria in pregnant women. 78 pregnant and 22 non-pregnant women with malarial infection (60% Plasmodium vivax and 40% P. falciparum) were included in the study. The results were analysed according to period of gestation, parity and type of infection. Severity of clinical illness was significantly higher in pregnant patients for both P. vivax and P. falciparum infections. Some striking differences were found in our study when compared with those from African countries. Multigravidas had a slightly higher morbidity than primigravidas, though the difference was not statistically significant. Even though only a small proportion (1.4%) of our pregnant patients were affected by malaria, cerebral malaria, maternal deaths, intrauterine foetal deaths and pre-term labours were much more common.
1984年6月至1985年11月，在印度北部开展了一项基于医院的前瞻性研究，以研究孕妇疟疾的发病模式。该研究纳入了78名感染疟疾的孕妇和22名感染疟疾的非孕妇（间日疟原虫感染占60%，恶性疟原虫感染占40%）。根据妊娠期、产次和感染类型对结果进行了分析。对于间日疟原虫和恶性疟原虫感染，孕妇的临床疾病严重程度均显著更高。与非洲国家的研究结果相比，我们的研究发现了一些显著差异。经产妇的发病率略高于初产妇，尽管差异无统计学意义。尽管我们的孕妇中只有一小部分（1.4%）感染了疟疾，但脑型疟疾、孕产妇死亡、宫内胎儿死亡和早产却更为常见。
