Pietrangelo Tiziana, Bondi Danilo, Kinel Edyta, Verratti Vittore
Department of Neuroscience, Imaging e Clinical Sciences, Università degli Studi "G. d'Annunzio" Chieti - Pescara, Chieti, Italy.
Department of Rehabilitation and Physiotherapy, Clinic of Rehabilitation, University of Medical Sciences, Poznań, Poland.
Front Physiol. 2019 Jan 14;9:1944. doi: 10.3389/fphys.2018.01944. eCollection 2018.
The phenomenon of strength gain is highly relevant for sarcopenia and clinical aspect linked to aging. Recent advancements drive the interest toward the exercise-related cross-talk between distant tissues. We demonstrated the cross-talk between lower and upper limbs, we named the Bottom-Up Rise Strength Transfer (BURST), mainly linked to endurance training. In our opinion, this effect can be mainly related to systemic factors, likely circulating myokines and extracellular vesicles (recently defined in terms of "exerkines" and "exersomes") whit an eventual concomitant reduction of a sub-clinical chronic inflammation. The neuronal mechanisms, even if to our sight less likely involved in this adaptation, need to be deeply investigated. Further studies are needed to better characterize the exercise-related BURST, concerning the specificity of different protocols and the underlying physiological mechanisms.
力量增强现象与肌肉减少症以及与衰老相关的临床方面高度相关。最近的进展引发了人们对远距离组织之间与运动相关的相互作用的兴趣。我们证明了下肢和上肢之间的相互作用，我们将其命名为自下而上的力量转移（BURST），主要与耐力训练有关。我们认为，这种效应可能主要与全身因素有关，可能是循环中的肌动蛋白和细胞外囊泡（最近分别定义为“运动因子”和“运动小体”），最终伴随亚临床慢性炎症的减轻。神经元机制，即使在我们看来不太可能参与这种适应性变化，但仍需要深入研究。需要进一步的研究来更好地描述与运动相关的BURST，涉及不同方案的特异性和潜在的生理机制。
