Norfolk and Norwich University Hospital National Health Service Foundation Trust, Norwich, United Kingdom.
Norwich Clinical Trials Unit, Norwich Medical School, University of East Anglia, Norwich, United Kingdom.
Laryngoscope. 2019 Oct;129(10):2384-2390. doi: 10.1002/lary.27841. Epub 2019 Jan 28.
OBJECTIVES/HYPOTHESIS: To determine the effectiveness of eye movement desensitization and reprocessing (EMDR) as a treatment for tinnitus.
Single-site prospective interventional clinical trial at a university hospital in the United Kingdom.
Participants were provided with tEMDR. This is a bespoke EMDR protocol that was developed specifically to treat individuals with tinnitus. Participants received a maximum of 10 sessions of tEMDR. Outcome measures including tinnitus questionnaires and mood questionnaires were recorded at baseline, discharge, and at 6 months postdischarge.
Tinnitus Handicap Inventory and Beck Depression Inventory scores demonstrated a statistically significant improvement at discharge after EMDR intervention (P = .0005 and P = .0098, respectively); this improvement was maintained at 6 months postdischarge. There was also a moderate but not significant (P = .0625) improvement in Beck Anxiety Inventory scores.
This study has demonstrated that the provision of tEMDR has resulted in a clinically and statistically significant improvement in tinnitus symptoms in the majority of those participants who took part. Furthermore, the treatment effect was maintained at 6 months after treatment ceased. This study is of particular interest, as the study protocol was designed to be purposefully inclusive of a diverse range of tinnitus patients. However, as a small uncontrolled study, these results do not consider the significant effects of placebo and therapist interaction. Larger high-quality studies are essential for the verification of these preliminary results.
4 Laryngoscope, 129:2384-2390, 2019.
目的/假设：确定眼动脱敏再处理（EMDR）作为耳鸣治疗方法的有效性。
英国一家大学医院的单站点前瞻性干预性临床试验。
为参与者提供 tEMDR。这是一种专门为治疗耳鸣患者而开发的定制 EMDR 方案。参与者最多接受 10 次 tEMDR。在基线、出院时和出院后 6 个月记录耳鸣问卷和情绪问卷等结果测量指标。
EMDR 干预后，耳鸣残疾量表和贝克抑郁量表评分显示出统计学上的显著改善（P = 0.0005 和 P = 0.0098，分别）；这种改善在出院后 6 个月仍得以维持。贝克焦虑量表评分也有适度但不显著的改善（P = 0.0625）。
这项研究表明，提供 tEMDR 治疗后，大多数参与者的耳鸣症状在临床和统计学上都有显著改善。此外，治疗效果在治疗停止后 6 个月仍得以维持。这项研究特别有趣，因为研究方案旨在有意纳入各种不同的耳鸣患者。然而，作为一项小型非对照研究，这些结果并未考虑安慰剂和治疗师互动的显著影响。需要更大规模的高质量研究来验证这些初步结果。
4.《喉镜》，129：2384-2390，2019 年。
