Sobouti Behnam, Momeni Mahnoush, Masalegooyan Niusha, Ansari Iman, Rahbar Hossein
Pediatric Infectious Disease, Burn Research Center, Iran University of Medical Sciences Tehran, Iran.
General Surgery, Burn Research Center, Iran University of Medical Sciences Tehran, Iran.
Int J Burns Trauma. 2018 Dec 20;8(6):149-152. eCollection 2018.
This is a relative rare case of 0.5% TBSA (total body surface area) burn wound infection caused by Herpes Simplex Virus (HSV). A 1-year-old male infant had deep second degree burn of the left fourth finger with 0.5% TBSA after exposure to a hot object. Blisters and vesicles surrounded by erythema were obvious in the examination of the burned area. The polymerase chain reaction (PCR) and gene sequencing analyses addressed contamination of the burn wound with HSV. Three days after the administration of antibiotics, the wound was relatively healed and finally, the patient was discharged in good general health, and no signs of relapse were observed in the 3-month follow-up. Although HSV infection is rarely reported in non-immunocompromised patients and TBSA burn injuries, due to the high prevalence of HSV infection and its mortality potential in the affected patients, HSV infection should be clinically suspected in the cases with delayed wound healing. In addition, since HSV infection is very contagious, and exposure to patients with HSV infection might be highly problematic for other patients hospitalized in burn wards; hence, proper facilities should be provided for the isolation care of the burn patients with HSV infection.
这是一例由单纯疱疹病毒（HSV）引起的相对罕见的病例，烧伤创面感染面积占总体表面积（TBSA）的0.5%。一名1岁男婴在接触热物体后，左手无名指出现深二度烧伤，烧伤面积占TBSA的0.5%。烧伤部位检查可见明显的水疱和红斑环绕的小水疱。聚合酶链反应（PCR）和基因测序分析表明烧伤创面存在HSV污染。使用抗生素三天后，创面相对愈合，最终患者健康状况良好出院，在3个月的随访中未观察到复发迹象。尽管在非免疫功能低下患者和TBSA烧伤中HSV感染很少见，但由于HSV感染患病率高且对受影响患者有潜在致死性，对于创面愈合延迟的病例应临床怀疑HSV感染。此外，由于HSV感染具有高度传染性，对于烧伤病房中其他住院患者而言，接触HSV感染患者可能会带来很大问题；因此，应为感染HSV 的烧伤患者提供适当的隔离护理设施。
