Omar Takrouni Arwa, Heitham Schammut Mohammad, Al-Otaibi Mishal, Al-Mulla Manal, Privitera Antonio
Department of General Surgery, Ministry of Health, Dammam, Eastern Province, Saudi Arabia.
BMJ Case Rep. 2019 Jan 29;12(1):e225054. doi: 10.1136/bcr-2018-225054.
Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. An 18-year-old woman presented to the emergency department with an obstructing caecal mass initially suspected to be malignant. Surgical resection was complicated by bowel perforation, histology and cultures confirmed basidiobolomycosis infection. The postoperative course was complicated by an enterocutaneous fistula, fungal intra-abdominal abscesses, liver and lung abscesses, formation of mycotic hepatic artery aneurysm and meningoencephalitis. The patient eventually expired due to sepsis despite aggressive treatment. Diagnosis and management of such rare cases are very challenging and require a multidisciplinary approach. Complications are common and associated with a high mortality.
担子菌病是一种罕见的真菌感染,可能会影响胃肠道。它由[具体病因未给出]引起,文献报道的病例少于80例。中东地区,特别是沙特阿拉伯的发病率似乎更高,该国大多数病例在西南部地区被诊断出来。一名18岁女性因盲肠肿块阻塞就诊于急诊科,最初怀疑为恶性肿瘤。手术切除因肠穿孔而复杂化,组织学和培养结果证实为担子菌病感染。术后病程因肠皮肤瘘、真菌性腹腔脓肿、肝和肺脓肿、霉菌性肝动脉瘤形成和脑膜脑炎而复杂化。尽管进行了积极治疗,患者最终因败血症死亡。诊断和管理此类罕见病例极具挑战性,需要多学科方法。并发症很常见,且死亡率很高。