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NCTN 评估放射组学在肿瘤学中的当前应用。

NCTN Assessment on Current Applications of Radiomics in Oncology.

机构信息

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.

出版信息

Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):302-315. doi: 10.1016/j.ijrobp.2019.01.087. Epub 2019 Jan 31.

DOI:10.1016/j.ijrobp.2019.01.087
PMID:30711529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6499656/
Abstract

Radiomics is a fast-growing research area based on converting standard-of-care imaging into quantitative minable data and building subsequent predictive models to personalize treatment. Radiomics has been proposed as a study objective in clinical trial concepts and a potential biomarker for stratifying patients across interventional treatment arms. In recognizing the growing importance of radiomics in oncology, a group of medical physicists and clinicians from NRG Oncology reviewed the current status of the field and identified critical issues, providing a general assessment and early recommendations for incorporation in oncology studies.

摘要

放射组学是一个快速发展的研究领域,基于将标准的医疗成像转化为可量化的挖掘数据,并建立后续的预测模型,以实现个体化治疗。放射组学已被提议作为临床试验概念中的研究目标,以及在介入治疗臂中对患者进行分层的潜在生物标志物。在认识到放射组学在肿瘤学中的重要性日益增加的情况下,NRG 肿瘤学的一组医学物理学家和临床医生回顾了该领域的现状,并确定了关键问题,为肿瘤学研究中的纳入提供了总体评估和早期建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9114/6499656/bf020e16f91e/nihms-1526147-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9114/6499656/bf020e16f91e/nihms-1526147-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9114/6499656/bf020e16f91e/nihms-1526147-f0001.jpg

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Radiother Oncol. 2018 Nov;129(2):218-226. doi: 10.1016/j.radonc.2018.06.025. Epub 2018 Jul 4.
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Early tumor response prediction for lung cancer patients using novel longitudinal pattern features from sequential PET/CT image scans.
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