Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.
Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):302-315. doi: 10.1016/j.ijrobp.2019.01.087. Epub 2019 Jan 31.
Radiomics is a fast-growing research area based on converting standard-of-care imaging into quantitative minable data and building subsequent predictive models to personalize treatment. Radiomics has been proposed as a study objective in clinical trial concepts and a potential biomarker for stratifying patients across interventional treatment arms. In recognizing the growing importance of radiomics in oncology, a group of medical physicists and clinicians from NRG Oncology reviewed the current status of the field and identified critical issues, providing a general assessment and early recommendations for incorporation in oncology studies.
放射组学是一个快速发展的研究领域,基于将标准的医疗成像转化为可量化的挖掘数据,并建立后续的预测模型,以实现个体化治疗。放射组学已被提议作为临床试验概念中的研究目标,以及在介入治疗臂中对患者进行分层的潜在生物标志物。在认识到放射组学在肿瘤学中的重要性日益增加的情况下,NRG 肿瘤学的一组医学物理学家和临床医生回顾了该领域的现状,并确定了关键问题,为肿瘤学研究中的纳入提供了总体评估和早期建议。