Keck School of Medicine, University of Southern California, Los Angeles, USA; Sadalla Amin Ghanem Eye Hospital, Joinville, SC, Brazil.
Keck School of Medicine, University of Southern California, Los Angeles, USA; Department of Ophthalmology, Tel Aviv Souraski Medical Center, Tel Aviv, Israel; Tel Aviv University, Tel Aviv, Israel.
J Cataract Refract Surg. 2019 Apr;45(4):490-494. doi: 10.1016/j.jcrs.2018.11.015. Epub 2019 Jan 31.
To compare higher order aberrations (HOAs) in normal eyes between a Scheimpflug imaging system (Pentacam HR) and dual Scheimpflug-Placido imaging system (Galilei G4).
Emory University, Atlanta, Georgia, and the University of Southern California, Los Angeles, USA.
Retrospective case series.
Eyes screened for refractive surgery were evaluated sequentially using a Scheimpflug device and a dual Scheimpflug-Placido device. Differences, correlations, and agreement between values for total root mean square (RMS), trefoil, coma, and spherical aberration were analyzed, and Bland-Altman plots were generated.
One hundred five eyes of 105 patients (44 men, 61 women) were evaluated. Total RMS, coma, and trefoil were significantly different between groups (all P < .001), while spherical aberration values were not. There was moderate correlation between devices for trefoil (r = 0.475 to 0.652), coma (r = 0.574 to 0.651), and spherical aberration (r = 0.483) and a strong correlation for total cornea RMS (r = 0.817). There was no directional bias between groups. The 95% limits of agreement for absolute values was 0.039 μm for trefoil at 30 degrees, 0.405 μm for trefoil at 0 degree, 0.553 μm for horizontal coma, 0.545 μm for vertical coma, 0.318 μm for spherical aberration, and 0.617 μm for RMS.
A Scheimpflug imaging device and dual Scheimpflug-Placido imaging device generated statistically different values for total cornea HOAs; however, the correlation between devices was moderate to strong and there was reasonable agreement in all measures for normal eyes. Based on these findings, the devices appear functionally equivalent for clinical use, although caution is warranted for outcomes-based research protocols that report HOAs.
比较眼前节断层成像系统（Pentacam HR）和双重 Scheimpflug-Placido 成像系统（Galilei G4）测量正常眼高阶像差（HOA）的差异。
美国佐治亚州亚特兰大市埃默里大学和加利福尼亚州洛杉矶市南加州大学。
回顾性病例系列研究。
对拟行屈光手术的患者进行筛查，使用眼前节断层成像系统和双重 Scheimpflug-Placido 成像系统依次进行评估。分析两组总均方根（RMS）、三叶、彗差和球差的差异、相关性和一致性，并生成 Bland-Altman 图。
共评估 105 例（44 例男性，61 例女性）105 只眼。两组间总 RMS、彗差和三叶差异均有统计学意义（均 P<0.001），而球差差异无统计学意义。两种设备之间三叶（r=0.4750.652）、彗差（r=0.5740.651）和球差（r=0.483）相关性中等，总角膜 RMS 相关性较强（r=0.817）。两组间无方向性偏倚。绝对差值的 95%一致性界限为：30 度时三叶的 0.039μm、0 度时三叶的 0.405μm、水平彗差的 0.553μm、垂直彗差的 0.545μm、球差的 0.318μm 和 RMS 的 0.617μm。
眼前节断层成像设备和双重 Scheimpflug-Placido 成像设备测量正常眼的总角膜 HOA 存在统计学差异，但两种设备的相关性中等至较强，所有指标的一致性较好。基于这些发现，两种设备在临床上似乎具有同等功能，尽管对于报告 HOA 的基于结果的研究方案需要谨慎。
