Gim Yujin, Jun Roo Min, Han Kyung Eun
Institute of Ophthalmology and Optometry, Department of Ophthalmology, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Institute of Ophthalmology and Optometry, Department of Ophthalmology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2021 Oct;35(5):337-348. doi: 10.3341/kjo.2021.0076. Epub 2021 Jul 8.
To evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measured by the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION.
This prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatism and its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments were compared. To compare the mean values of the measurements, a paired t-test was used. Bland-Altman analysis was applied to assess the agreement between the two devices.
Fifty-three eyes of 53 subjects were evaluated. There were statistically significant differences for steep K, astigmatism, and vector J0, J45 in the anterior surface and total corneal power between the two devices (p < 0.05). There were also significant differences in the most of the keratometric values of the posterior corneal surface (p < 0.05) except J0 (p = 0.410). Both devices showed strong positive correlations in steep K, flat K, astigmatism (r > 0.81, p < 0.001) with wide ranges of a 95% limit of agreement. Vectoral components were significantly correlated (r > 0.78, p < 0.001) with narrow 95% limit of agreement, except J45 of the posterior surface (r = 0.39, p = 0.004). In the corneal HOAs, there were statistically significant differences in the vertical coma, horizontal trefoil, spherical aberration, and root mean square of each fifth- and sixth-order Zernike coefficient (p = 0.043, p = 0.041, p < 0.001, p < 0.001, and p < 0.001, respectively). Other HOAs showed moderate to strong positive correlations (r > 0.37, p < 0.05). Most HOAs, except for the horizontal trefoil, showed clinically acceptable agreements. The total root mean square of HOAs was not significantly different between the two devices (p = 0.122).
Most of the keratometric values cannot be used interchangeably. However, the vectoral component of astigmatism showed clinically good agreement. Several HOAs have statistically significant differences; however, almost all HOAs showed acceptable agreements, except for the horizontal trefoil.
评估通过眼前节分析系统Pentacam HR和扫频源光学相干断层扫描ANTERION测量的角膜曲率、散光和高阶像差（HOA）的兼容性。
这项前瞻性研究纳入了无眼科病史的正常受试者。比较了使用这两种仪器测量的陡峭角膜曲率（K）、平坦K值、散光及其前后表面的轴、总角膜屈光力和HOA。为比较测量的平均值，采用配对t检验。应用Bland-Altman分析评估两种设备之间的一致性。
对53名受试者的53只眼进行了评估。两种设备在前表面的陡峭K值、散光以及矢量J0、J45和总角膜屈光力方面存在统计学显著差异（p<0.05）。除J0（p = 0.410）外，后表面的大多数角膜曲率值也存在显著差异（p<0.05）。两种设备在陡峭K值、平坦K值、散光方面均显示出强正相关性（r>0.81，p<0.001），一致性界限范围较宽。矢量分量显著相关（r>0.78，p<0.001），一致性界限范围较窄，但后表面的J45除外（r = 0.39，p = 0.004）。在角膜HOA方面，垂直彗差、水平三叶草像差、球差以及各五阶和六阶泽尼克系数的均方根存在统计学显著差异（分别为p = 0.043、p = 0.041、p<0.001、p<0.001和p<0.001）。其他HOA显示出中度至强正相关性（r>0.37，p<0.05）。除水平三叶草像差外，大多数HOA显示出临床可接受的一致性。两种设备之间HOA的总均方根无显著差异（p = 0.122）。
大多数角膜曲率值不能互换使用。然而，散光的矢量分量显示出良好的临床一致性。几种HOA存在统计学显著差异；然而，除水平三叶草像差外，几乎所有HOA都显示出可接受的一致性。
