Thorgeirsson Gestur, Masdottir Birna Bjorg, Gudnason Thorarinn, Heimisdottir Maria
Department of Internal Medicine, Division of Cardiology, Landspitali - The National University Hospital of Iceland, Faculty of Medicine, University of Iceland.
Department of Finance and Information, Landspitali - The National University Hospital of Iceland.
Laeknabladid. 2019 Feb;105(2):79-84. doi: 10.17992/lbl.2019.02.217.
Marked changes in the epidemiology of acute coronary syndromes (ACS) have been observed over the last few decades in the Western Hemisphere. Incidence rates of ACS in Iceland 2003-2012 are presented.
All patients with unstable angina (UA), non ST-elevation myocardial infarction (NSTEMI) and ST-elevation myocardial infarc-tion (STEMI) admitted to Landspitali were included in the study. Data were obtained from hospital records and changes during the period were examined.
The total number of ACS cases was 7,502. STEMI incidence was reduced from 98/100,000 inhabitants in 2003 to 63 in 2012, a reduction of nearly 36%. Age standardized incidence rates of STEMI declined annually by 5.5% in men and 5.3% in women (p <0.05). Incidence of NSTEMI increased from 54 /100,000 inhabitants in 2003 to 93 in 2012. UA patients were 56/100,000 inhabitants in 2003, 115 in 2008 and 50 in 2012. No significant annual change in age-standardized incidence rates of NSTEMI and UA was observed. About 35% of patients with NSTEMI and 30% with STEMI and UA were female. The mean age of NSTEMI patients was 72 years, five years higher than patients with STEMI and UA. About 30% of -pat-ients were living outside of the capital region.
2003-2012 there was a significant 5% annual -decrease in the number of STEMI cases and a tendency to -increasing incidence of NSTEMI which by the end of the research period was the most common of the syndromes. An unusual development in the incidence of UA was observed. Possible effect of psychological stress in the society should be considered.
在过去几十年中，西半球急性冠状动脉综合征（ACS）的流行病学出现了显著变化。本文呈现了冰岛2003年至2012年ACS的发病率。
纳入所有入住冰岛国家大学医院的不稳定型心绞痛（UA）、非ST段抬高型心肌梗死（NSTEMI）和ST段抬高型心肌梗死（STEMI）患者。数据来自医院记录，并对该期间的变化进行了检查。
ACS病例总数为7502例。STEMI发病率从2003年的每10万居民98例降至2012年的63例，降幅近36%。STEMI的年龄标准化发病率男性每年下降5.5%，女性每年下降5.3%（p<0.05）。NSTEMI发病率从2003年的每10万居民54例增至2012年的93例。2003年UA患者为每10万居民56例，2008年为115例，2012年为50例。未观察到NSTEMI和UA年龄标准化发病率的显著年度变化。约35%的NSTEMI患者以及30%的STEMI和UA患者为女性。NSTEMI患者的平均年龄为72岁，比STEMI和UA患者高5岁。约30%的患者居住在首都地区以外。
2003年至2012年，STEMI病例数每年显著下降5%，NSTEMI发病率有上升趋势，到研究期末NSTEMI成为最常见的综合征。观察到UA发病率出现异常变化。应考虑社会心理压力可能产生的影响。
