Ahmed Mohammed Rifaat, Abou-Halawa Ashraf Saad, Hessam Waheed F, Abdelkader Diaa' Salaheldin Aly
Faculty of Medicine, Department of Otolaryngology, Suez Canal University, Ismailia, Egypt.
Faculty of Medicine, Department of Microbiology and Immunology, Suez Canal University, Ismailia, Egypt.
Interv Med Appl Sci. 2018 Sep;10(3):145-149. doi: 10.1556/1646.10.2018.28.
Otomycosis is a common ear problem in countries with hot and humid climate. Emergence of new fungal species is a possibility particularly in patients with chronic illness or who receives antibiotics either systemically or topically.
To identify the otomycotic species, which are responsible for developing the otomycosis.
A descriptive study was carried out in 63 patients who were clinically diagnosed with otomycosis. Swabs were taken from the fungal debris to identify the causative agent and to determine the effective antifungals against it.
species were the most common agents and were found in 47 patients (74.6%), represented by (36.5%), (27%), (6.5%), and (4.8%). Ketoconazole (90%) and miconazole (76%) were the most effective antifungals against the species obtained from cultures, whereas fluconazole was the least effective.
Although there is no change in the mycology of otomycosis, there is still a significant variability in the isolated species and in their sensitivity to antifungal drugs. Ketoconazole exhibited broad spectrum effect against fungal isolates in this study, whereas fluconazole was the least efficacious.
在气候炎热潮湿的国家，耳真菌病是一种常见的耳部疾病。新真菌种类的出现是有可能的，特别是在患有慢性病或全身或局部使用抗生素的患者中。
鉴定导致耳真菌病的耳真菌种类。
对63例临床诊断为耳真菌病的患者进行了描述性研究。从真菌残渣中采集拭子，以鉴定病原体并确定针对其有效的抗真菌药物。
是最常见的病原体，在47例患者（74.6%）中发现，其中 占（36.5%）， 占（27%）， 占（6.5%）， 占（4.8%）。酮康唑（90%）和咪康唑（76%）是对培养获得的菌种最有效的抗真菌药物，而氟康唑效果最差。
虽然耳真菌病的真菌学没有变化，但分离出的菌种及其对抗真菌药物的敏感性仍存在显著差异。在本研究中，酮康唑对真菌分离株表现出广谱作用，而氟康唑效果最差。
