囊泡和隧道介导的蛋白质运输。
Protein transport by vesicles and tunnels.
机构信息
Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain
Universitat Pompeu Fabra, Barcelona, Spain.
出版信息
J Cell Biol. 2019 Mar 4;218(3):737-739. doi: 10.1083/jcb.201811073. Epub 2019 Feb 4.
Abstract
Palade's corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport intermediates that can be vesicles and transient direct tunnels.
摘要
帕拉德的小体被认为是蛋白质在稳定的分泌途径不同隔室之间运输的唯一途径。我们认为，货物、分泌隔室的空间组织以及充满货物的容器分裂的时间决定了运输中间物的设计，可以是小泡和瞬时直接隧道。
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