芦荟科植物叶乳胶对革兰氏阳性和革兰氏阴性细菌菌株的抗菌潜力
Antibacterial Potential of (Aloeacea) Leaf Latex against Gram-Positive and Gram-Negative Bacteria Strains.
作者信息
Emiru Yohannes Kelifa, Siraj Ebrahim Abdela, Teklehaimanot Tekleab Teka, Amare Gedefaw Getnet
机构信息
School of Pharmacy, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
School of Pharmacy, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
出版信息
Int J Microbiol. 2019 Jan 2;2019:5328238. doi: 10.1155/2019/5328238. eCollection 2019.
OBJECTIVE
To evaluate the antibacterial effects of the leaf latex of against infectious bacterial strains.
METHODS
The leaf latex of at different concentrations (400, 500, and 600 mg/ml) was evaluated for antibacterial activities using the disc diffusion method against some Gram-negative species such as (ATCC 14700) and (ATCC 35619) and Gram-positive such as (ATCC 50080) and (ATCC 4623).
RESULTS
The tested concentrations of the latex ranging between 400 and 600 mg·mL showed significant antibacterial activity against bacterial strain. The highest dose (600 mg/ml) of leaf latex revealed the maximum activity (25.93 ± 0.066 inhibition zone) followed by the dose 500 mg/ml against The lowest antibacterial activity was observed by the concentration 400 mg/ml (5.03 ± 0.03) against .
CONCLUSION
The results of the present investigation suggest that the leaf latex of can be used as potential leads to discover new drugs to control some bacterial infections.
目的
评估[植物名称]叶乳胶对感染性细菌菌株的抗菌作用。
方法
采用纸片扩散法，针对一些革兰氏阴性菌如[细菌名称1]（ATCC 14700）和[细菌名称2]（ATCC 35619）以及革兰氏阳性菌如[细菌名称3]（ATCC 50080）和[细菌名称4]（ATCC 4623），评估不同浓度（400、500和600mg/ml）的[植物名称]叶乳胶的抗菌活性。
结果
测试浓度在400至600mg·mL之间的乳胶对细菌菌株显示出显著的抗菌活性。[植物名称]叶乳胶的最高剂量（600mg/ml）显示出最大活性（抑菌圈为25.93±0.066），其次是500mg/ml的剂量对[细菌名称]。400mg/ml的浓度对[细菌名称]观察到最低的抗菌活性（5.03±0.03）。
结论
本研究结果表明，[植物名称]叶乳胶可作为发现控制某些细菌感染新药的潜在先导物。
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