School of medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Department of medical laboratory Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
BMC Infect Dis. 2019 Feb 6;19(1):118. doi: 10.1186/s12879-019-3753-5.
More than 50% of the people are infected worldwide with H. pylori which causes significant public health morbidity and mortality. The distribution is quite different from country to country. Hence, early information is very important to prevent upper gastrointestinal complications. The current study aimed to assess the magnitude of H. pylori and associated risk factors among symptomatic patients attending at Jasmin internal medicine and pediatrics specialized private clinic from August 2017 until May 2018 in Addis Ababa city, Ethiopia.
A cross-sectional study was conducted among 487 patients with upper gastrointestinal tract complaints attending at Jasmin internal medicine and pediatrics specialized private clinic from August 2017 until May 2018. Convenient sampling technique was used to enroll participants. Information regarding to risk factors was assessed using structured questionnaire. Stool samples were collected for H. pylori antigen test. Data was entered and analyzed using SPSS version20 statistical software and a p-value less than 0.05 was considered as statistically significant.
The overall prevalence of H. pylori among participants using stool antigen was 36.8% (n = 179/487). Regarding to family income status, those who have low monthly income were more likely to be infected with H. pylori infection (AOR = 6.056, CI 95% = 1.603-22.881, P = 0.037). In addition, families with low educational level were more likely to be infected with H. pylori infection than higher level education (AOR = 4.150, CI95% = 1.059-16.270, P = 0.041). Number of family members in the house-hold, type of toilet they used and source of drinking water were not significantly associated with H. pylori infection.
The prevalence of H. pylori infection was 36.8% and it was related to low income and low education levels. This finding calls for improving the socioeconomic status of the community. Moreover, further studies are needed to investigate potential risk factors for H. pylori infection.
全球超过 50%的人感染了幽门螺杆菌，这导致了严重的公众健康发病率和死亡率。这种分布在不同国家之间有很大的差异。因此，早期的信息对于预防上消化道并发症非常重要。本研究旨在评估 2017 年 8 月至 2018 年 5 月期间在埃塞俄比亚亚的斯亚贝巴市 Jasmin 内科和儿科专科私人诊所就诊的有上消化道症状的患者中幽门螺杆菌的感染率及其相关危险因素。
这是一项横断面研究，研究对象为 2017 年 8 月至 2018 年 5 月期间在 Jasmin 内科和儿科专科私人诊所就诊的有上消化道症状的 487 名患者。采用便利抽样技术招募参与者。使用结构化问卷评估与危险因素相关的信息。采集粪便样本进行幽门螺杆菌抗原检测。使用 SPSS 版本 20 统计软件输入和分析数据，p 值小于 0.05 被认为具有统计学意义。
使用粪便抗原检测，参与者中幽门螺杆菌的总体感染率为 36.8%（n=179/487）。就家庭收入状况而言，那些月收入较低的人更有可能感染幽门螺杆菌（OR=6.056，95%CI=1.603-22.881，P=0.037）。此外，文化程度较低的家庭比文化程度较高的家庭更有可能感染幽门螺杆菌（OR=4.150，95%CI=1.059-16.270，P=0.041）。家庭人口数、使用的厕所类型和饮用水来源与幽门螺杆菌感染无显著相关性。
幽门螺杆菌感染率为 36.8%，与低收入和低教育水平有关。这一发现呼吁改善社区的社会经济地位。此外，还需要进一步研究以调查幽门螺杆菌感染的潜在危险因素。
