Ouvrard C, Meillon C, Dartigues J-F, Tabue Teguo M, Avila-Funes J A, Amieva H
Camille Ouvrard, Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, F-33000 Bordeaux, France, 146 Rue Léo Saignat, 33076 Bordeaux cedex, France, Tel: +33 5 57 57 11 73, Fax: +33 5 57 57 14 86, Mail to:
J Frailty Aging. 2019;8(1):42-47. doi: 10.14283/jfa.2018.36.
Low socioeconomic status and frailty are factors of vulnerability in old age. They are both well-known risk factors of death. On the other hand, low socioeconomic status has been reported as a predictor of frailty, which questions the relationship between socioeconomic status, frailty and death.
The aim of this work was to explore the respective contribution of psychosocioeconomic precariousness - which covers socioeconomic status and also psychosocial vulnerability - and frailty in predicting mortality.
Prospective population-based study.
Three-City (3C) Bordeaux study, France.
The sample consisted of 1586 subjects aged 65 or older.
Psychosocioeconomic precariousness was assessed utilizing a structured instrument which assessed poor socioeconomic status, and psychosocial vulnerability. Frailty status was defined by Fried's phenotype.
After 14 years of follow-up, 665 deaths (42%) occurred. Psychosocioeconomic precariousness and frailty had both an independent contribution to mortality prediction (hazard ratio (HR) 1.51 (95% confidence interval (CI) 1.11-2.07)) and (HR 1.68 (95% CI 1.19-2.38)), respectively. Such relationships were adjusted for age, sex, disability, and comorbidities. No interaction term was found between precariousness and frailty.
If psychosocioeconomic precariousness and frailty are both aspects of vulnerability in old age, they have a non-overlapping contribution in the prediction of mortality. These findings emphasize the importance of considering both psychosocioeconomic precariousness and frailty when identifying elderly people at risk of death.
社会经济地位低下和身体虚弱是老年易损性的因素。它们都是众所周知的死亡风险因素。另一方面,社会经济地位低下已被报道为身体虚弱的一个预测因素,这对社会经济地位、身体虚弱和死亡之间的关系提出了质疑。
这项研究的目的是探讨心理社会经济不稳定——涵盖社会经济地位以及心理社会易损性——和身体虚弱在预测死亡率方面各自的作用。
基于人群的前瞻性研究。
法国波尔多三市(3C)研究。
样本包括1586名65岁及以上的受试者。
使用一种结构化工具评估心理社会经济不稳定,该工具评估社会经济地位低下和心理社会易损性。身体虚弱状态由弗里德表型定义。
经过14年的随访,发生了665例死亡(42%)。心理社会经济不稳定和身体虚弱在死亡率预测中都有独立的作用(风险比(HR)分别为1.51(95%置信区间(CI)1.11 - 2.07))和(HR 1.68(95% CI 1.19 - 2.38))。这些关系针对年龄、性别、残疾和合并症进行了调整。未发现不稳定和虚弱之间的交互项。
如果心理社会经济不稳定和身体虚弱都是老年易损性的方面,那么它们在死亡率预测中具有不重叠的作用。这些发现强调了在识别有死亡风险的老年人时同时考虑心理社会经济不稳定和身体虚弱的重要性。