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Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling.干细胞静止：活力、约束与细胞空闲。
Cell Stem Cell. 2019 Feb 7;24(2):213-225. doi: 10.1016/j.stem.2019.01.001.
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Mechanisms, Hallmarks, and Implications of Stem Cell Quiescence.干细胞静止的机制、特征及意义。
Stem Cell Reports. 2019 Jun 11;12(6):1190-1200. doi: 10.1016/j.stemcr.2019.05.012.
3
Stem cell quiescence: the challenging path to activation.干细胞静止：激活的艰难之路。
Development. 2021 Feb 8;148(3):dev165084. doi: 10.1242/dev.165084.
4
Molecular regulation of stem cell quiescence.干细胞静止的分子调控。
Nat Rev Mol Cell Biol. 2013 Jun;14(6):329-40. doi: 10.1038/nrm3591.
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Molecular Regulation of Cellular Quiescence: A Perspective from Adult Stem Cells and Its Niches.细胞静止的分子调控：来自成体干细胞及其微环境的视角
Methods Mol Biol. 2018;1686:1-25. doi: 10.1007/978-1-4939-7371-2_1.
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Mimicking Muscle Stem Cell Quiescence in Culture: Methods for Synchronization in Reversible Arrest.在培养中模拟肌肉干细胞静止状态：可逆性停滞同步化方法
Methods Mol Biol. 2017;1556:283-302. doi: 10.1007/978-1-4939-6771-1_15.
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Quiescence Entry, Maintenance, and Exit in Adult Stem Cells.成体干细胞的静息进入、维持和退出。
Int J Mol Sci. 2019 May 1;20(9):2158. doi: 10.3390/ijms20092158.
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Lysosomes and signaling pathways for maintenance of quiescence in adult neural stem cells.溶酶体和信号通路在维持成年神经干细胞静息中的作用。
FEBS J. 2021 May;288(10):3082-3093. doi: 10.1111/febs.15555. Epub 2020 Sep 15.
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The mini-IDLE 3D biomimetic culture assay enables interrogation of mechanisms governing muscle stem cell quiescence and niche repopulation.迷你 IDLE 3D 仿生培养分析可用于研究调控肌肉干细胞静息和龛位再填充的机制。
Elife. 2022 Dec 20;11:e81738. doi: 10.7554/eLife.81738.
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Dormancy and quiescence of skeletal muscle stem cells.骨骼肌干细胞的休眠与静止
Results Probl Cell Differ. 2015;56:215-35. doi: 10.1007/978-3-662-44608-9_10.
引用本文的文献
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Quiescence Multiverse.静止多元宇宙。
Biomolecules. 2025 Jul 4;15(7):960. doi: 10.3390/biom15070960.
2
Generation of mature epicardium derived from human-induced pluripotent stem cells via inhibition of mTOR signaling.通过抑制mTOR信号通路从人诱导多能干细胞生成成熟心外膜。
Nat Commun. 2025 Jul 1;16(1):5902. doi: 10.1038/s41467-025-60934-8.
3
Reversible proliferative arrest induced by rapid depletion of RNase MRP.核糖核酸酶MRP快速耗竭诱导的可逆性增殖停滞
Nat Commun. 2025 Jun 18;16(1):5342. doi: 10.1038/s41467-025-60471-4.
4
GPNMB marks a quiescent cell population in melanoma and promotes metastasis formation.GPNMB标记黑色素瘤中的静止细胞群并促进转移形成。
EMBO Rep. 2025 Jun 17. doi: 10.1038/s44319-025-00501-w.
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Heat Preconditioning of Nanofat Does Not Improve Its Vascularization Properties.纳米脂肪的热预处理并不能改善其血管化特性。
Cells. 2025 Apr 11;14(8):581. doi: 10.3390/cells14080581.
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Physical training reduces cell senescence and associated insulin resistance in skeletal muscle.体育锻炼可减少骨骼肌中的细胞衰老及相关的胰岛素抵抗。
Mol Metab. 2025 May;95:102130. doi: 10.1016/j.molmet.2025.102130. Epub 2025 Mar 22.
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Metabolic Objectives and Trade-Offs: Inference and Applications.代谢目标与权衡：推断与应用
Metabolites. 2025 Feb 6;15(2):101. doi: 10.3390/metabo15020101.
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Role of the NuRD complex and altered proteostasis in cancer cell quiescence.核小体重塑去乙酰化酶复合物（NuRD complex）的作用及蛋白质稳态改变在癌细胞静止中的作用
bioRxiv. 2025 Feb 14:2025.02.10.637435. doi: 10.1101/2025.02.10.637435.
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Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer.鉴定MRTFA/SRF信号通路是癌症中静止状态的关键调节因子。
bioRxiv. 2024 Nov 17:2024.11.15.623825. doi: 10.1101/2024.11.15.623825.
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A latent Axin2/Scx progenitor pool is the central organizer of tendon healing.潜在的Axin2/Scx祖细胞池是肌腱愈合的核心组织者。
NPJ Regen Med. 2024 Oct 17;9(1):30. doi: 10.1038/s41536-024-00370-2.
本文引用的文献
1
Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain.细胞类型特异性分析鉴定了小鼠大脑中受调控的蛋白异构体变化。
Cell Rep. 2019 Jan 15;26(3):594-607.e7. doi: 10.1016/j.celrep.2018.12.077.
2
Cellular localization of the cell cycle inhibitor Cdkn1c controls growth arrest of adult skeletal muscle stem cells.细胞周期抑制剂 Cdkn1c 的细胞定位控制成年骨骼肌干细胞的生长停滞。
Elife. 2018 Oct 4;7:e33337. doi: 10.7554/eLife.33337.
3
Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.多能造血干细胞的层次相关谱系限制命运。
Nature. 2018 Feb 1;554(7690):106-111. doi: 10.1038/nature25455. Epub 2018 Jan 3.
4
Revealing age-related changes of adult hippocampal neurogenesis using mathematical models.利用数学模型揭示成年海马体神经发生与年龄相关的变化。
Development. 2018 Jan 8;145(1):dev153544. doi: 10.1242/dev.153544.
5
Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo.体内静止肌肉干细胞的转录谱分析。
Cell Rep. 2017 Nov 14;21(7):1994-2004. doi: 10.1016/j.celrep.2017.10.037.
6
In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells.原位固定重新定义了骨骼肌干细胞的静息和早期激活。
Cell Rep. 2017 Nov 14;21(7):1982-1993. doi: 10.1016/j.celrep.2017.10.080.
7
Cell-type-specific metabolic labeling of nascent proteomes in vivo.体内新生蛋白质组的细胞类型特异性代谢标记。
Nat Biotechnol. 2017 Dec;35(12):1196-1201. doi: 10.1038/nbt.4016. Epub 2017 Nov 6.
8
Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence.Staufen1 通过抑制 MyoD 翻译来积极维持肌肉干细胞静止状态。
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E8996-E9005. doi: 10.1073/pnas.1708725114. Epub 2017 Oct 9.
9
Controlling Depth of Cellular Quiescence by an Rb-E2F Network Switch.通过 Rb-E2F 网络开关控制细胞静止深度。
Cell Rep. 2017 Sep 26;20(13):3223-3235. doi: 10.1016/j.celrep.2017.09.007.
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Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis.生物正交蛋白质组标记在细胞移植和异时联体共生中的应用。
Nat Commun. 2017 Sep 21;8(1):643. doi: 10.1038/s41467-017-00698-y.
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