CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China; University of Chinese Academy of Sciences, Beijing 100049, China.
CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Infect Genet Evol. 2019 Apr;69:224-229. doi: 10.1016/j.meegid.2019.02.001. Epub 2019 Feb 6.
Bats are the natural reservoirs of severe acute respiratory syndrome coronavirus (SARS-CoV) which caused the outbreak of human SARS in 2002-2003. We introduce the genetic diversity of SARS-related coronaviruses (SARSr-CoVs) discovered in bats and provide insights on the bat origin of human SARS. We also analyze the viral geographical structure that may improve our understanding of the evolution of bat SARSr-CoVs.
蝙蝠是严重急性呼吸系统综合征冠状病毒（SARS-CoV）的天然宿主，该病毒于 2002-2003 年引发了人类 SARS 疫情。我们介绍了在蝙蝠中发现的与 SARS 相关的冠状病毒（SARSr-CoVs）的遗传多样性，并就人类 SARS 的蝙蝠起源提供了一些见解。我们还分析了病毒的地理结构，这可能有助于我们理解蝙蝠 SARSr-CoVs 的进化。
