Department of Dermatology, Haydarpasa Numune Training and Research Hospital, University of Medical Sciences, Tibbiye Cd. No: 23 Uskudar, 34668, Istanbul, Turkey.
Department of Dermatology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
Intern Emerg Med. 2019 Aug;14(5):699-703. doi: 10.1007/s11739-019-02039-x. Epub 2019 Feb 8.
Pathergy phenomenon is a non-specific tissue hyperreactivity reaction due to trauma and is a minor diagnostic criterion of Behcet's disease. In this study, 100 patients with a suspicion of Behcet's disease who were referred to Cerrahpasa Medical Faculty Dermatology department between 01.11.2014 and 31.01.2015 are included. Skin pathergy tests were applied to all the patients and results were evaluated by two dermatologists separately at 48th hour, each with naked eye and with dermatoscopy. Test results were scored on a scale of 0-6. At the end of the study, score results of naked eye and dermatoscopy for doctor number 1 were statistically similar. Same results applied for doctor number 2. However, naked eye results of doctor number 1 and 2 for the same patients were significantly different from each other (p 0.0372) and with dermatoscopy examination this difference was eliminated (p > 0.05). This study revealed that naked eye evaluation of pathergy test results can yield different results among different interpreters. Use of dermatoscopy during the evaluation process decreases interobserver variation and subjectivity of the test.
现象是一种非特异性组织高反应性反应，由于创伤，是一个次要的诊断标准的白塞病。在这项研究中，100 例怀疑白塞病患者被转诊到 Cerrahpasa 医疗faculty 皮肤科部门之间 01.11.2014 和 31.01.2015。皮肤试验应用于所有的患者和结果进行评估由两个皮肤科医生分别在 48 小时，每个用肉眼和皮肤镜。试验结果评分 0-6 分。在研究结束时，得分结果的肉眼和皮肤镜医生 1 统计相似。相同的结果适用于医生 2。然而，医生 1 和 2 之间的肉眼结果相同的病人有显著差异（p 0.0372）和皮肤镜检查，这种差异被消除（p > 0.05）。本研究表明，肉眼评估的试验结果可以产生不同的结果之间的不同解释。在评价过程中使用皮肤镜可以减少观察者间的变异和测试的主观性。
