Minh Phuong Pham Thi, Bich Diep Dang, Hai Van Nguyen Thi, Van Thuong Nguyen, Cam Van Tran, Khang Tran Hau, Gandolfi Marco, Satolli Francesca, Feliciani Claudio, Tirant Michael, Vojvodic Aleksandra, Lotti Torello
National Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Dermatology and Venereology Faculty, Hanoi Medical University, Vietnam.
Open Access Maced J Med Sci. 2019 Jan 29;7(2):293-297. doi: 10.3889/oamjms.2019.098. eCollection 2019 Jan 30.
To evaluate the effectiveness and safety of micro-needling therapy in atrophic acne scar treatment.
A prospective, single centred study was implemented in a total of 31 patients suffering from atrophic acne scar grade 2 to 4 of Goodman and Baron scaring grading system was recruited. They were treated by microneedle derma roller every week in 3 months. The scars were evaluated by a magic system camera and by dermatologists clinically using Goodman and Baron scaring grading system, and Lipper and Perez score at baseline, at final treatment, 1 month and 2 months after the final treatment.
The results showed improvement in all patients. The mean of Goodman and Barron's grade was decreased from 3.29 ± 0.59 at baseline, 2.23 ± 0.56 at final treatment, 1.93 ± 0.58 one month after the completion of therapy and to 1.77 ± 0.57 two months after the completion of therapy (with the p-value < 0.05). Similarly, Lipper and Perez score also dropped significantly from 36.48 ± 12.07 at baseline to 23.16 ± 15.01 at final treatment, to 17.83 ± 7.00 one month after the final treatment and to 16.37 ± 7.29 at two months after the final treatment (p-value < 0.05). Skin roughness and hyperpigmented spots got improved significantly. History of having nodular-cystic or vulgaris acne did not affect the effectiveness of the therapy. Side effects of the therapy were burning sensation, erythema but they were very mild and recovered in 1-2 days. No severe complication and post-inflammatory hyperpigmentation were noted. 83.3% of the patients satisfied after the completion of the therapy.
Skin needling is an effective and safe method for the treatment of atrophic acne scars.
评估微针疗法治疗萎缩性痤疮瘢痕的有效性和安全性。
对31例采用古德曼和巴伦瘢痕分级系统评定为2至4级的萎缩性痤疮瘢痕患者进行了一项前瞻性单中心研究。在3个月内，他们每周接受微针滚针治疗。在基线期、治疗结束时、治疗结束后1个月和2个月，通过魔镜系统相机以及皮肤科医生使用古德曼和巴伦瘢痕分级系统、利珀和佩雷斯评分对瘢痕进行评估。
结果显示所有患者均有改善。古德曼和巴伦分级的平均值从基线时的3.29±0.59降至治疗结束时的2.23±0.56、治疗结束后1个月的1.93±0.58以及治疗结束后2个月的1.77±0.57（p值<0.05）。同样，利珀和佩雷斯评分也从基线时的36.48±12.07显著降至治疗结束时的23.16±15.01、治疗结束后1个月的17.83±7.00以及治疗结束后2个月的16.37±7.29（p值<0.05）。皮肤粗糙度和色素沉着斑明显改善。有结节囊肿性痤疮或寻常痤疮病史并不影响治疗效果。治疗的副作用为烧灼感、红斑，但非常轻微，1 - 2天内恢复。未观察到严重并发症和炎症后色素沉着。83.3%的患者在治疗结束后表示满意。
皮肤微针疗法是治疗萎缩性痤疮瘢痕的一种有效且安全的方法。
