依库珠单抗成功治疗一例伴发的溶血性尿毒症综合征。
Successful treatment of a associated haemolytic uraemic syndrome by eculizumab.
作者信息
Jeantet Guillaume, Pernin Vincent, Brunot Vincent, Roccabianca Arnaud, Macombe Anouk, Szwarc Ilan, Klouche Kada, Loirat Chantal, Mourad Georges, Frémeaux-Bacchi Véronique, Le Quintrec Moglie
机构信息
Department of Nephrology and Kidney Transplantation, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.
Critical Care Department, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.
出版信息
Clin Kidney J. 2019 Feb;12(1):106-109. doi: 10.1093/ckj/sfy019. Epub 2018 Mar 20.
Haemolytic uraemic syndrome (HUS) is a rare complication of invasive infection by (SP-HUS), especially in adults. Here we report an unusual case of a 53-year-old man presenting SP-HUS with severe multivisceral involvement. After failure of supportive care and plasma exchanges, eculizumab (anti-C5 antibody) resulted in a favourable outcome.
溶血性尿毒症综合征（HUS）是由[具体病原体]引起的侵袭性感染的一种罕见并发症（特别是在成人中），尤其是由[具体病原体]引起的（典型溶血尿毒综合征，SP-HUS）。在此，我们报告一例不寻常的病例，一名53岁男性出现伴有严重多脏器受累的SP-HUS。在支持治疗和血浆置换失败后，依库珠单抗（抗C5抗体）带来了良好的治疗效果。
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