Department of Mechanical Engineering, University College London, London, UK.
Department of Metallurgical and Materials Engineering, University of Marmara, Istanbul, Turkey.
Int Wound J. 2019 Jun;16(3):730-736. doi: 10.1111/iwj.13090. Epub 2019 Feb 15.
Cinnamon-containing polycaprolactone (PCL) bandages were produced by pressurised gyration and their anti-fungal activities against Candida albicans were investigated. It was found that by preparing and spinning polymer solutions of cinnamon with PCL, fibres capable of inhibiting fungal growth could be produced, as observed in disk diffusion tests for anti-fungal susceptibility. Fascinatingly, compared with raw cinnamon powder, the novel cinnamon-loaded fibres had outstanding long-term activity. The results presented here are very promising and may indeed accelerate a new era of using completely natural materials in biomedical applications, especially in wound healing.
含肉桂的聚己内酯（PCL）绷带通过加压旋转生产，并研究了其对白色念珠菌的抗真菌活性。结果发现，通过将肉桂与 PCL 制备和纺丝成聚合物溶液，可以生产出能够抑制真菌生长的纤维，这在抗真菌药敏性的圆盘扩散试验中得到了观察。有趣的是，与原始肉桂粉相比，新型负载肉桂的纤维具有出色的长期活性。这里呈现的结果非常有希望，实际上可能加速在生物医学应用中使用完全天然材料的新时代，特别是在伤口愈合方面。
