Hwang Ho Sik, Kim Eun Chul, Kim Man Soo, Yang Suk-Woo
Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon, South Korea.
Department of Ophthalmology, Bucheon St. Mary's Hospital, Catholic University of Korea, Bucheon, South Korea.
BMC Ophthalmol. 2019 Feb 18;19(1):53. doi: 10.1186/s12886-019-1064-7.
To demonstrate that the Corvis ST could be used to quantify the biomechanical parameters of the orbital soft tissues by measuring and comparing whole eye movement (WEM) using the Corvis in normal eyes and in eyes of patients with Graves ophthalmopathy.
Forty four eyes of 44 ophthalmologically normal subjects and 28 eyes of 28 patients with Graves ophthalmopathy were included in the study. After Corvis test, the examiners recorded WEM by air puff. In the patients with Graves ophthalmopathy, the partial correlation coefficient adjusted for age and gender was calculated to analyze the correlation between exopthalmometry and WEM. Same analysis was repeated for the correlation between and the cross sectional area (%) of the extraocular muscles in the orbit CT and WEM.
WEM was 0.314 ± 0.083 mm in the normal subjects and 0.227 ± 0.079 mm in the Graves ophthalmopathy group (p = 0.000). The exophthalmometry was not significantly correlated with WEM after adjusting for age and gender (R = 0.083, p = 0.688). In the 21 Graves ophthalmopathy patients examined by orbit CT, after adjusting for age and gender, WEM significantly decreased as the cross sectional area (%) of the extraocular muscles in the orbit increased (R = - 0.461, p = 0.047).
WEM by Corvis could be used to quantify the biomechanical parameters of the orbital soft tissue. However, it is unclear whether WEM effectively represents the orbital biomechanical parameters, because WEM is only 0.6% of the orbital depth.
通过使用Corvis测量和比较正常眼睛及格雷夫斯眼病患者眼睛的全眼运动（WEM），以证明Corvis ST可用于量化眼眶软组织的生物力学参数。
本研究纳入了44名眼科正常受试者的44只眼睛和28名格雷夫斯眼病患者的28只眼睛。在进行Corvis测试后，检查者通过吹气记录WEM。在格雷夫斯眼病患者中，计算经年龄和性别调整后的偏相关系数，以分析眼球突出度与WEM之间的相关性。对眼眶CT中眼外肌横截面积（%）与WEM之间的相关性进行同样的分析。
正常受试者的WEM为0.314±0.083mm，格雷夫斯眼病组为0.227±0.079mm（p = 0.000）。经年龄和性别调整后，眼球突出度与WEM无显著相关性（R = 0.083，p = 0.688）。在21名接受眼眶CT检查的格雷夫斯眼病患者中，经年龄和性别调整后，随着眼眶中眼外肌横截面积（%）的增加，WEM显著降低（R = -0.461，p = 0.047）。
Corvis测量的WEM可用于量化眼眶软组织的生物力学参数。然而，尚不清楚WEM是否能有效代表眼眶生物力学参数，因为WEM仅为眼眶深度的0.6%。
