Department of Ophthalmology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, China.
BMC Ophthalmol. 2024 Aug 28;24(1):382. doi: 10.1186/s12886-024-03635-y.
To investigate the correlation between whole eye movement (WEM) parameters measured using Corvis ST and axial length (AL) to explore whether AL affects WEMs.
This single-center, cross-sectional study included data from healthy subjects and patients preparing for refractive surgery at the Qingdao Eye Hospital of Shandong First Medical University. Data were collected from July 2021 to April 2022. We first determined the correlations of WEMs at the time of corneal first applanation (A1_WEM), highest concavity (HC_WEM), and second applanation (A2_WEM), as well as the maximum value of WEM (WEM_Max) with AL. Subsequently, we established a series of regression models to analyze the relationships between different WEM values and AL.
AL was negatively correlated with HC_WEM, A2_WEM, and WEM_Max (r = - 0.28, - 0.23, and - 0.22, respectively; P < 0.001). The correlation between AL and A1_WEM was not significant (P = 0.77). According to the adjusted regression models, AL was negatively associated with HC_WEM (Model 2: β = -7.39, P < 0.001) and WEM_Max (Model 4: β = -3.52, P = 0.02), while the associations of AL with A1_WEM (Model 1: P = 0.61) and A2_WEM (Model 3: P = 0.23) were not significant.
AL is an independent negative influencing factor for HC_WEM. WEM is a potentially useful parameter that reflects the biomechanical properties of the eye behind the cornea in myopia.
探讨应用 Corvis ST 测量的全眼运动（WEM）参数与眼轴（AL）的相关性，以探究 AL 是否影响 WEM。
本单中心、横断面研究纳入了山东第一医科大学青岛眼科医院准备接受屈光手术的健康受试者和患者的数据。数据收集于 2021 年 7 月至 2022 年 4 月。我们首先确定了角膜首次压平（A1_WEM）、最大凹陷（HC_WEM）和第二次压平（A2_WEM）时的 WEM 以及 WEM 最大值（WEM_Max）与 AL 的相关性。随后，我们建立了一系列回归模型来分析不同 WEM 值与 AL 的关系。
AL 与 HC_WEM、A2_WEM 和 WEM_Max 呈负相关（r 值分别为-0.28、-0.23 和-0.22；P 值均<0.001）。AL 与 A1_WEM 的相关性不显著（P=0.77）。根据调整后的回归模型，AL 与 HC_WEM 呈负相关（模型 2：β=-7.39，P<0.001）和 WEM_Max 呈负相关（模型 4：β=-3.52，P=0.02），而 AL 与 A1_WEM（模型 1：P=0.61）和 A2_WEM（模型 3：P=0.23）的相关性不显著。
AL 是 HC_WEM 的独立负影响因素。WEM 是反映角膜后近视眼生物力学特性的一个潜在有用的参数。
