Ro 17-2301及其他抗菌剂对耐头孢噻肟需氧革兰氏阴性杆菌的抗菌活性。
Antibacterial activity of Ro 17-2301 and other antimicrobial agents against cefotaxime-resistant aerobic gram-negative bacilli.
作者信息
Benson C A, Walton F E, Trenholme G M
出版信息
Antimicrob Agents Chemother. 1986 Jan;29(1):155-7. doi: 10.1128/AAC.29.1.155.
Abstract
The in vitro activity of Ro 17-2301 was determined and compared with those of aztreonam, ceftazidime, amikacin, and piperacillin against 141 cefotaxime-resistant gram-negative bacilli. Ro 17-2301 was bactericidal, and its activity against the majority of these organisms was equal or superior to those of ceftazidime, aztreonam, and piperacillin. An inoculum effect of Ro 17-2301 and aztreonam for many Pseudomonas aeruginosa and Enterobacter spp. isolates was demonstrated.
摘要
测定了Ro 17-2301对141株耐头孢噻肟革兰阴性杆菌的体外活性，并与氨曲南、头孢他啶、阿米卡星和哌拉西林进行了比较。Ro 17-2301具有杀菌作用，其对大多数这些菌株的活性等同于或优于头孢他啶、氨曲南和哌拉西林。已证实Ro 17-2301和氨曲南对许多铜绿假单胞菌和肠杆菌属菌株具有接种物效应。
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