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将Ro 17-2301和氨曲南与其他新型β-内酰胺类抗生素对铜绿假单胞菌临床分离株的体外活性进行比较。

In vitro activities of Ro 17-2301 and aztreonam compared with those of other new beta-lactam antibiotics against clinical isolates of Pseudomonas aeruginosa.

作者信息

Ng W W, Chau P Y, Leung Y K, Livermore D M

出版信息

Antimicrob Agents Chemother. 1985 May;27(5):872-3. doi: 10.1128/AAC.27.5.872.

Abstract

The in vitro activities of Ro 17-2301 and aztreonam against 191 Pseudomonas aeruginosa isolates were compared with those of five other beta-lactam antibiotics. Both compounds showed activities comparable to that of ceftazidime and were bactericidal. They were as effective against gentamicin-or carbenicillin-resistant isolates as against susceptible ones.

摘要

将Ro 17-2301和氨曲南对191株铜绿假单胞菌分离株的体外活性与其他五种β-内酰胺类抗生素进行了比较。这两种化合物的活性与头孢他啶相当,且具有杀菌作用。它们对庆大霉素或羧苄西林耐药的分离株与对敏感分离株一样有效。

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1
In vitro activity of carumonam.卡芦莫南的体外活性。
Antimicrob Agents Chemother. 1985 Dec;28(6):834-6. doi: 10.1128/AAC.28.6.834.
2
Aztreonam concentration in abdominal tissues and bile.氨曲南在腹部组织和胆汁中的浓度。
Antimicrob Agents Chemother. 1986 Jun;29(6):1101-3. doi: 10.1128/AAC.29.6.1101.

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