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及时治疗改善预后:要求:6周内首次就诊

[Improvement of prognosis by timely treatment : Requirement: initial presentation within 6 weeks].

作者信息

Lorenz H-M, Wendler J, Krause A

机构信息

Klinik für Hämatologie, Onkologie und Rheumatologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Deutschland.

Internistische Praxisgemeinschaft Rheumatologie - Nephrologie, Erlangen, Deutschland.

出版信息

Z Rheumatol. 2019 Jun;78(5):396-403. doi: 10.1007/s00393-019-0607-x.

Abstract

Rheumatoid arthritis (RA) is one of the most frequent chronic inflammatory rheumatic diseases and when untreated leads to chronic tissue destruction and increased mortality. Due to innovative systemic treatment strategies established over the last 20-25 years, the prognosis has considerably improved in terms of disease and socioeconomic burdens, symptoms, long-term prognosis, ability to work and mortality; however, as a rule a prerequisite is long-term and continuous treatment. A medicinal cure of RA is still not in view. For many patients this means the long-term use of very expensive medications. In addition to hemato-oncology, rheumatology has become the second most expensive discipline in Germany in terms of cost per patient. Convincing data from many studies imply that an early start of treatment within the first few weeks after clinical onset of symptoms improves the prognosis, reduces the necessity for expensive drugs and thereby considerably decreases medical costs. This results in the requirement that every patient with symptoms of arthritis must be seen by a rheumatologist within the first 6 weeks following initial manifestation of the disease. Such an improvement in treatment can only be achieved in Germany if the numbers of rheumatologists and trained healthcare professionals in practices such as clinics are considerably increased. This is not only in the interests of patients but also in the interests of the health insurance companies because the investment in the healthcare infrastructure with internistic rheumatologists will result in substantial economic benefits for the cost bearer. It must be the common task of all players in healthcare policy, cost bearers and internistic rheumatologists to provide optimal conditions in medical as well as economical terms.

摘要

类风湿关节炎(RA)是最常见的慢性炎症性风湿性疾病之一,若不治疗会导致慢性组织破坏并增加死亡率。由于过去20至25年建立的创新全身治疗策略,在疾病负担、社会经济负担、症状、长期预后、工作能力和死亡率方面,预后有了显著改善;然而,通常长期持续治疗是一个先决条件。RA的药物治愈仍未实现。对许多患者来说,这意味着长期使用非常昂贵的药物。除血液肿瘤学外,就每位患者的费用而言,风湿病学已成为德国第二昂贵的学科。许多研究的令人信服的数据表明,在症状临床发作后的头几周内尽早开始治疗可改善预后,减少使用昂贵药物的必要性,从而大幅降低医疗成本。这就要求每位有关节炎症状的患者在疾病首次出现后的6周内必须由风湿病学家诊治。只有在德国大幅增加风湿病学家以及诊所等机构中经过培训的医疗保健专业人员数量,才能实现这种治疗改善。这不仅符合患者的利益,也符合健康保险公司的利益,因为投资于有内科风湿病学家的医疗基础设施将为费用承担者带来巨大的经济效益。在医疗和经济方面提供最佳条件,必须是医疗保健政策的所有参与者、费用承担者和内科风湿病学家的共同任务。

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