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关于表面疏水性在脑膜炎奈瑟菌黏附颊上皮细胞中的作用的研究。

Studies on the implication of surface hydrophobicity in the adherence of Neisseria meningitidis to buccal epithelial cells.

作者信息

Criado M T, Ferreiros C M, Sainz V

出版信息

Med Microbiol Immunol. 1986;175(1):27-34. doi: 10.1007/BF02123126.

DOI:10.1007/BF02123126
PMID:3083219
Abstract

The study of surface hydrophobicity and adherence to human buccal epithelial cells of four Neisseria meningitidis strains and the correlation analysis of the data obtained for both parameters has demonstrated that hydrophobicity of meningococci is not a causative factor in adherence in normal conditions. Modification of the bacterial surfaces (by freezing, heating, ultraviolet irradiation, fixation with glutaraldehyde or sodium metaperiodate cleavage of external sugars) induced significant changes in one or both parameters, but these changes were not correlative in both properties. In contrast to other bacteria, the hydrophobicity levels shown by our meningococci are not relevant to their adherent processes.

摘要

对4株脑膜炎奈瑟菌的表面疏水性及其对人颊上皮细胞的黏附性进行研究,并对这两个参数的数据进行相关性分析,结果表明,在正常情况下,脑膜炎球菌的疏水性并非黏附的致病因素。细菌表面的修饰(通过冷冻、加热、紫外线照射、用戊二醛固定或用高碘酸钠裂解外部糖类)导致一个或两个参数发生显著变化,但这两个特性的变化并无相关性。与其他细菌不同,我们所研究的脑膜炎球菌的疏水性水平与其黏附过程无关。

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本文引用的文献

1
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Infect Immun. 1981 Jan;31(1):430-5. doi: 10.1128/iai.31.1.430-435.1981.
2
The effect of sublethal injury by heating, freezing, drying and gamma-radiation on the duration of the lag phase of Salmonella typhimurium.加热、冷冻、干燥及γ射线辐射造成的亚致死损伤对鼠伤寒沙门氏菌迟缓期持续时间的影响。
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Cellular adhesion: description, methodology and drug perturbation.
墨西哥亚马逊利什曼原虫的表面自由能。
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Surface charge and hydrophobicity of wild and mutant Crithidia fasciculata.野生型和突变型纤细短膜虫的表面电荷与疏水性
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Differences in the adhesive properties of Neisseria meningitidis for human buccal epithelial cells and erythrocytes.脑膜炎奈瑟菌对人颊上皮细胞和红细胞黏附特性的差异。
Infect Immun. 1983 Jul;41(1):106-13. doi: 10.1128/iai.41.1.106-113.1983.
5
Effect of subinhibitory concentrations of antimicrobials on meningococcal adherence.亚抑菌浓度抗菌药物对脑膜炎球菌黏附的影响。
Can J Microbiol. 1983 Mar;29(3):369-76. doi: 10.1139/m83-061.
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J Infect Dis. 1981 Apr;143(4):525-32. doi: 10.1093/infdis/143.4.525.
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