Kamiński Bartłomiej
Department of Otolaryngology, Maria Skłodowska-Curie District Hospital in Skarżysko-Kamienna, Poland.
Reumatologia. 2019;57(1):37-44. doi: 10.5114/reum.2019.83237. Epub 2019 Feb 28.
Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and a range of extra-glandular features. The most common and earliest symptoms are oral and ocular dryness. The aim of this study is to present the most common otolaryngological manifestations of SS, their pathomechanism and possible aetiology. The most common oral signs and symptoms are xerostomia, tooth decay, fungal infections, traumatic oral lesions, dysphagia, dysgeusia, and inflammation of the salivary glands. The salivary glands of SS patients are characterised by chronic inflammation. The presence of foci is thus a hallmark of SS. A biopsy can be taken from either the labial or the parotid salivary gland. The most significant complication of SS is the development of lymphoproliferative malignancy, which occurs in about 5% of SS patients. The ultrasonic greyscale scoring system, glandular volume measurement, and intraglandular power Doppler ultrasonography are specific ultrasound parameters of SS.
干燥综合征（SS）是一种全身性自身免疫性疾病，其特征为外分泌腺淋巴细胞浸润以及一系列腺体外表现。最常见且最早出现的症状是口腔和眼部干燥。本研究的目的是介绍干燥综合征最常见的耳鼻喉科表现、其发病机制及可能的病因。最常见的口腔体征和症状包括口干、龋齿、真菌感染、口腔创伤性病变、吞咽困难、味觉障碍以及唾液腺炎症。干燥综合征患者的唾液腺以慢性炎症为特征。因此，病灶的存在是干燥综合征的一个标志。活检可取自唇腺或腮腺。干燥综合征最严重的并发症是淋巴增殖性恶性肿瘤的发生，约5%的干燥综合征患者会出现这种情况。超声灰阶评分系统、腺体体积测量以及腺体内功率多普勒超声检查是干燥综合征特定的超声参数。
